Tatyana V. Sokolova, Uladzimir P. Adaskevich, Alexander P. Malyarchuk, Yulia V. Lopatina

Conclusion: This is the description of a rare clinical form of scabies, scabious erythroderma. It is based on the analysis of the 5 cases of scabies, whose main clinical manifestation is diffuse erythroderma. The diagnostic criteria of scabious erythroderma and differential diagnosis of Norwegian scabies are given. The invasive potential of this form of the disease on the patient and beyond is evaluated for the first time.

Frederick N. Bebe, Shasa Hu, Tony L. Brown, Orien L. Tulp

Conclusion: This study confirms well-established race/ethnicity, gender and age disparities in metastatic melanoma diagnosis – majority white and male, and majority of the cases between ages 56 and 71. However, unlike previous studies, laterality was evenly-distributed and majority of AA and HW were diagnosed with moderately or poorly-differentiated tumors.

Edoardo Torres – Guerrero, Claudia Jessica Espinoza – Hernández, Stephanie Arroyo – Camarena, Carlos Enrique Atoche – Diéguez

Microsporum gypseum has a wide world distribution however clinical cases due to this agent are scarce. This is one of the largest compilations of clinical cases due to this pathogen. Students and housewives were the main affected. It could be due to play on the ground, contact with pets, or domestic duties.

Funda Tamer

Syphilis is an infectious disease characterized by various mucocutaneous and systemic findings. It can mimic many other diseases. Therefore, syphilis is known as ‘the great imitator’. It remains a public health problem especially in developing countries. Treatment of the early stages of syphilis is fast, easy and effective. However, it can result in serious complications if left untreated. Therefore, early diagnosis is crucial. Hereby, a 30-year-old Caucasian female with an oral syphilis who had previously been misdiagnosed was presented. Syphilis can be easily misdiagnosed in patients with oral mucosal lesions. It should be considered in the differential diagnosis of other intraoral diseases.

Case Report

Delayed diagnosis of radiation – associated cutaneous angiosarcoma

Nina Korsaga/Somé, Nayi Zongo, Thibault Kervarrec, Aurélie Sallot, Alexandre Penaud, Gonzague de Pinieux, Laurent Machet

Angiosarcoma is most frequently occurring in patients treated for a previous cancer with radiation therapy. Our aim was to measure the time between the first signs found by the patient and the first biopsy, and the time before the final diagnosis of radiation-associated angiosarcoma (RAAS) and to analyse the reasons for delayed diagnosis. Four patients met the inclusion criteria. Three had cutaneous RAAS and one had suprapubic cutaneous RAAS after treatment for cancer. The intervals between the first cutaneous sign recorded by the patient and the diagnosis of RAAS were 9 to 37 months. The initial diagnosis by the non-specialist pathologist was a benign vascular lesion. Review of the initial biopsy was consistent with RAAS in 3 cases and with AVL in 1 case. Clinicians should alert pathogists when a vascular lesion is larger than 5 mm in the context of irradiated skin. Histology review by an expert should be recommended.

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Case Report

Penile nodules revealing systemic amyloidosis associated with mieloma

Loubab Omahsan, Nassiba Zerrouki, Nada Zizi, Siham Dikhaye

Amyloidosis is a rare disease. Nodular cutaneous amyloidosis is the rarest clinical form of cutaneous amyloidosis. It may be associated with a systemic disease. We report an exceptional case of amyloidosis associated with myeloma, with a double atypical localization: Well-defined papulo-nodules of the base of the penis; Vertebral amyloidosis causing spinal cord compression. The association of nodular skin lesions to a myeloma should evoke the diagnosis of amyloidosis.

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Online Section

Coherence of clinical and histopathological diagnosis of most common skin lesions

Ewa Ziajka, Jan Błaszczyk

The study group consisted mostly of women (n = 429, 60.50%). The mean age in the study group was 49 years (Me=48). The histopathological assessment revealed more types of lesions than in the clinical procedure (73 vs. 38), in both cases the dye naevus was most common. Clinical and histopathological diagnosis differed in 398 cases (54.37% of the total). The highest percentage of correct diagnoses was obtained in basal cell carcinoma (BCC) (88.57%), actinic keratosis (77.72%) and dye naevus (58.19%). The worst coherence was found in case of hair cysts (0.00%), cell naevus (7.63%) and atypical dye naevus (19.05%). In 22 cases, the changes originally described as benign were finally diagnosed as pre-cancer conditions or cancers. Both cases of melanoma were diagnosed incorrectly.

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