Nandakishore Thokchom, Kapila Verma, Bishurul NA Hafi, Sandhyarani Kshetrimayum, Vanlalhriatpuii Hmar, Linda Kongbam, Nandita Bhattacharjee

Conclusion: This study demonstrates a strong association of thyroid disorders in certain conditions, such as vitiligo, alopecia areata, diffuse hair loss, dry skin, chronic urticaria, and melasma. Thus, the inclusion of thyroid function tests in routine investigations of these conditions would be helpful.

Adil Mellouki, Jauffray Oliva, Ouima Justin Dieudonné Ziba, Laurent Daniel, Eric Lechevallier, Michael Baboudjian

Conclusion: The treatment of metastatic melanoma is challenging. Although the genitourinary tract is a rare site of metastasis, early detection is important as effective therapies are available, improving control of local symptoms and the potential disease progression.

Veselina Belyova, Razvigor Darlenski

A 42-year-old Caucasian female patient presented with symmetric, asymptomatic, periorbital angioedema that appeared 24 hours after the second dose of the Moderna mRNA COVID-19 vaccine. She was injected with the hyaluronic acid dermal filler Juvéderm Volite in the glabella and periorbital area three months earlier and underwent a botulinum toxin session in the forehead, glabella, and crow’s feet with Vistabel six months earlier.

Ana Maria Abreu Velez, Bruce R Smoller, Michael S. Howard

Conclusion: We conclude that the roles of IgD, complement C4, and other inflammatory markers may indeed play critical roles in bullous SLE and that these markers might be included in the diagnostic and research panels employed to study autoimmune diseases. Furthermore, low complement C4 levels are frequently found in systemic lupus erythematosus; patient seric levels may also fluctuate, with low levels of both often seen in disease flare-ups. In our case, the patient displayed a normal seric acid titer (< 8.3 mg/dL; normal range < 10 mg/dL) [12]. Thus, we speculate that the autoimmune response to selected structures in the dermis (demonstrated by IHC staining) may contribute to a decrease in complement C4 levels in patients with bullous SLE.

Ahmed Abdul-Aziz Ahmed, Ghusoon Nazar Jaber

To the best of our knowledge, this is the first reported case of vitiligo associated with the administration of the Oxford–AstraZeneca (AZD1222) vaccine.

Santhanakrishnaan Soundarya, Srinivasan Sundaramoorthy

Conclusion: Because the world is now facing an emergency crisis due to the COVID-19 pandemic, protection is of paramount importance so as to control the spread of the virus. Washing hands multiple times a day and the use of sanitizers and masks have become a part of the daily routine. A proper knowledge of the skin and of the adverse effects of personal protective equipment (PPE) will help patients in fighting against the pandemic without interruption.
Healthcare workers are more prone to various dermatological complications arising from existing diseases as well as to new skin eruptions. Poverty and the socioeconomic loss to the community and the government should be properly and carefully calculated and addressed so as to minimize mortality and loss of life. The world should unite without politics to conquer the pandemic and to save as many human lives as possible.

Jerzy Lasek, Piotr Brzeziński

COVID-19 pandemic which started in 2019 dramatically influenced healthcare systems all over the world. This epidemic affected both epidemiology and organization of management in patients after severe trauma. In many countries emergency departments suddenly were put under pressure by an overwhelming number of patients with COVID-19 infection and with acute respiratory insufficiency requiring respirator therapy in intensive care units (ICU). In many countries special guidelines for COVID-19 management have been established. In general the aim of the guidelines is to preserve the hospital capacity for the patients following both major and minor trauma by means of reorganization of local health systems and providing optimal trauma care.