Our Dermatology Online, e-ISSN: 2081-9390
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Alexandra K. Alexandrova, Vera A. Smolyannikova, Varvara A. Filatova, Olga K. Alexandrova
Conclusions: The connection was found between the intensity of the p16 expression and the prevalence of SK. Given the presence of insulin resistance in the anamnesis of patients with multiple SK, an assumption was made about an indirect effect of the p16 expression on hyperinsulinemia. The presence of focal intense reactions with antibodies to p16 by patients with single SK can serve as a predictor of eruptions dissemination in future.
Patricia Chang, Kathia Domínguez
Conclusion: The alterations of finger and toe nails in the elderly are not exclusive of this group as they occur in the general population except that in the elderly, the most frequent are onychorrhexis in hands and onychogryphosis in feet.
Ewa Stocka-Łabno, Natalia Gabzdyl, Magdalena Misiak-Gałązka, Małgorzata Pawłowska-Kisiel, Tomasz Łazowski, Lidia Rudnicka
Conclusion: The study indicates that in observed population drugs with the highest risk of most severe reactions are lamotrigine (anticonvulsant) and antimicrobials (most commonly sulfonamides), therefore it is advisable to consider carefully administration of these drugs, especially to patients with history of autoimmune reactions.
Sebastian Boldt, Uwe Wollina
Abstract: Skin diseases can be a first sign of internal malignancies. Acrokeratosis neoplastica or Bazex-syndrome is a rare obligatory paraneoplastic dermatosis. We report on a 51-year-old male patient who complaint about reduced physical working capacity, swelling of fingers and toes. He presented with non-itching violaceous erythemato-squamous lesions on nose, hands and feet. On examination we observed onychomadesis of finger nails. Thoracic computerized tomography disclosed a tumor mass in the distal esophagus. Endosonography with trans-esophageal fine-needle biopsy confirmed the diagnosis of esophageal squamous cell carcinoma. The knowledge of cutaneous paraneoplasias allows an earlier diagnosis of internal malignancies.
Aboubacar H. Bambara , Amina N Ouedraogo, Nina A Ouedraogo Nde, Vincent B Ili, Jérôme Sanou, Achach Thouraya Chtioui, Tarticus Konsem
Abstract: Dermatofibrosarcoma protuberans (DFS) is a rare malignant skin tumor, characterized by local aggressiveness, significant potential for recurrence and a low risk of distant metastasis. The location under the eyes, not yet reported in the literature may involve the functional and aesthetic prognosis. We report a case.
Muriel Sidnoma Ouédraogo, Nina Korsaga/Somé, Aimé Sosthène Ouédraogo, Nomtondo Amina Ouédraogo, Gilbert Patrice Tapsoba, Tarcissus Konsem, Jean-Baptiste Andonaba, Jean Sakandé, Pascal Niamba, Adama Traoré
Abstract: Epidermoid carcinomas account for one third of cutaneous carcinomas. These are the most common cancers in adults. On dark skin, epidermoid carcinomas do not mainly occur on photo-exposed areas but rather complicate chronic ulcers. We are reporting the case of a 39 years old patient, HIV 1 positive being consulted for a budding tumor of the upper lip occurred on chronic erosion that appeared three years before. The histopathological examination of the bioptic specimen and of the resection specimen objectified a differentiated and mature epidermoid carcinoma. The patient was classified as Stage II: T3 N0 M 0. A complete tumor resection was performed followed by a double labial reconstruction by local advancement flap. Chronic ulceration and HIV infection have been identified as factors that favored malignant transformation. Limited access to health facilities has reportedly favored the evolution of lesions towards a complicated form and difficult medical care. The therapeutic challenge was to remove the tumor while preserving the function and aesthetics of the mouth.
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