since 05. April 2013
C O N T E N T S 2.2013
COMMENTS ON THE ARTICLES
ORIGINAL ARTICLES
Mykhailo Andreychyn, Dmytro Zhyvytsia
Effect of antiretroviral therapy on survival of HIV/TB-infected patients in Ukraine
Our Dermatol Online 2013; 4(2): 149-152 DOI: 10.7241/ourd.20132.34
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Iffat Hassan, Shazia Jeelani, Abid Keen, Mashkoor Wani
Classical fusiform excision of melanocytic nevi: our experience
Our Dermatol Online 2013; 4(2): 153-156 DOI: 10.7241/ourd.20132.35
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Neerja Puri, Asha Puri
A study on tinea capitis in the pre school and school going children
Our Dermatol Online 2013; 4(2): 157-160 DOI: 10.7241/ourd.20132.36
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Comment by: Dr. Rajesh Jeewon Ph.D.
Our Dermatol Online 2013; 4(2): 161 DOI: 10.7241/ourd.20132.36.1
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Neerja Puri, Asha Puri
A study on efficacy of oral zinc therapy for treatment of acrodermatitis enteropathica
Our Dermatol Online 2013; 4(2): 162-166 DOI: 10.7241/ourd.20132.37
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Comment by: Ass. Prof. Miloš Jeseňák
Our Dermatol Online 2013; 4(2): 167 DOI: 10.7241/ourd.20132.37.1
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CASE REPORTS
Ganesh Dhavalshankh, Archana Dhavalshankh, Vaishali Masvekar
Cutaneous manifestations of dermatomyositis in male patient: a rare report
Our Dermatol Online 2013; 4(2): 168-171 DOI: 10.7241/ourd.20132.38
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Leena Raveendra, Belliappa Pemmanda Raju, Umashankar Nagaraju, Vivekananda, Priya Kootelu Sundar, Lokanatha Keshavalu
Atrophic type of morphea profundus – an Indian experience
Our Dermatol Online 2013; 4(2): 172-175 DOI: 10.7241/ourd.20132.39
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Ajili Faida, Bousseta Najeh, Msakni Issam, Metoui Leila, Gharsallah Imen, Laabidi Janet, Ben Abdelhafidh Nadia, Louzir Bassem, Ammar Bouziani, Othmani Salah
Symptomatic macroglossia and tongue myositis in Dermatomyositis
Our Dermatol Online 2013; 4(2): 176-178 DOI: 10.7241/ourd.20132.40
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Parvaiz Anwar Rather, Iffat Hassan
Blaschkoid lichen planus in an adult Kashmiri male: a rare presentation
Our Dermatol Online 2013; 4(2): 179-182 DOI: 10.7241/ourd.20132.41
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Kanthilatha Pai, Sathish Pai
Zosteriform Lichen Planus: case report of a rare variant of Lichen Planus
Our Dermatol Online 2013; 4(2): 183-184 DOI: 10.7241/ourd.20132.42
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Uladzimir P. Adaskevich, Maryia A. Katina, Valeryia A. Miadzelets
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Comment by: Anca Chiriac MD, PhD and Prof. Caius Solovan
Our Dermatol Online 2013; 4(2): 188 DOI: 10.7241/ourd.20132.43.1
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Nwabudike Lawrence Chukwudi
Does pityriasis rosea Koebnerise?
Our Dermatol Online 2013; 4(2): 189-190 DOI: 10.7241/ourd.20132.44
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Comment by: Ass. Prof. Antonio Chuh and Prof. Vijay Zawar
Our Dermatol Online 2013; 4(2): 191 DOI: 10.7241/ourd.20132.44.1
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Ana Maria Abreu Velez, Isabel Cristina Avila, Michael S. Howard
Immune response in a cutaneous allergic drug reaction secondary to imidapril, benazapril and metformin
Our Dermatol Online 2013; 4(2): 192-195 DOI: 10.7241/ourd.20132.45
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Marko Vok
Recurrent postcoital fixed drug eruption caused by co-trimoxazole mimicking a sexually induced disease
Our Dermatol Online 2013; 4(2): 196-198 DOI: 10.7241/ourd.20132.46
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Ana Maria Abreu Velez, A. Deo Klein, Michael S. Howard
Specific cutaneous histologic and immunologic features in a case of early lupus erythematosus scarring alopecia
Our Dermatol Online 2013; 4(2): 199-203 DOI: 10.7241/ourd.20132.47
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Neerja Puri, Asha Puri
Strict anatomical co existence and colocalization of vitiligo and psoriasis – a rare entity
Our Dermatol Online 2013; 4(2): 202-204 DOI: 10.7241/ourd.20132.48
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Neerja Puri
Infantile psoriasis treated successfully with topical calcipotriene
Our Dermatol Online 2013; 4(2): 205-207 DOI: 10.7241/ourd.20132.49
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Belliappa Pemmanda Raju, Umashankar Nagaraju, Leena Raveendra, Vivekananda, Priya Kootelu Sundar, Lokanatha Keshavalu
Oculocutaneous albinism complicated with an ulcerated plaque
Our Dermatol Online 2013; 4(2): 208-211 DOI: 10.7241/ourd.20132.50
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Faten Limaiem, Sirine Bouslema, Inès Haddad, Fadoua Abdelmoula, Saâdia Bouraoui, Ahlem Lahmar, Sabeh Mzabi
Milia-like idiopathic calcinosis cutis of the medial canthus
Our Dermatol Online 2013; 4(2): 212-214 DOI: 10.7241/ourd.20132.51
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Maria Orsaria, Laura Mariuzzi
Recurrent eccrine hidradenoma of the breast in a male patient: problems in differential diagnosis
Our Dermatol Online 2013; 4(2): 215-217 DOI: 10.7241/ourd.20132.52
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Lakshmi Rao, Vidya Monappa, Mohammed Musheb
Cutaneous nodule on the face: adamantinoid trichoblastoma – a rare, unique tumor
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Chidambharam Choccalingam, Premila Samuel, Deepak Subramaniam, Faizal Hammed, PurushothamanV, Rajiv Joshi
Syringocystadenocarcinoma Papilliferum: A case report of a rare skin adnexal tumour
Our Dermatol Online 2013; 4(2): 221-223 DOI: 10.7241/ourd.20132.54
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Mohamed El Bouihi, Saad Lahmiti, Souad Aimadeddine, Ahmed Zaroual, Saad Fawzi, Nadia Mansouri Hattab
A columellar deformity caused by a congenital schwannoma
Our Dermatol Online 2013; 4(2): 224-225 DOI: 10.7241/ourd.20132.55
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Anca Chiriac, Cristina Birsan, Anca E. Chiriac, Tudor Pinteala, Liliana Foia
Hand, Foot and Mouth disease in northeastern part of Romania in 2012
Our Dermatol Online 2013; 4(2): 226-229 DOI: 10.7241/ourd.20132.56
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REVIEW ARTICLE
Beatriz Di Martino Ortiz
Claves para el diagnóstico dermatopatológico de los quistes cutáneos.
Dermatopathological clues for the diagnosis of skin cysts
Our Dermatol Online 2013; 4(2): 230-236 DOI: 10.7241/ourd.20132.57
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CLINICAL IMAGES
Max Carlos Ramírez Soto
Facial Sporotrichosis in children from endemic area in Peru
Our Dermatol Online 2013; 4(2): 237-240 DOI: 10.7241/ourd.20132.58
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LETTER TO THE EDITOR
Anca Chiriac, Anca E. Chiriac, Tudor Pinteala, Liliana Foia, Caius Solovan, Piotr Brzezinski
Petechiae- adverse reactions to Ciprofloxacin
Our Dermatol Online 2013; 4(2): 241-242 DOI: 10.7241/ourd.20132.59
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HISTORICAL ARTICLES
Khalid Al Aboud, Ahmad Al Aboud
Eponyms in dermatology literature linked to genital skin disorders
Our Dermatol Online 2013; 4(2): 243-246 DOI: 10.7241/ourd.20132.60
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Khalid Al Aboud, Ahmad Al Aboud
Eponyms in the dermatology literature linked to the oral disorders
Our Dermatol Online 2013; 4(2): 247-250 DOI: 10.7241/ourd.20132.61
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Khalid Al Aboud, Ahmad Al Aboud
Names of ”Lines” in dermatology literature
Our Dermatol Online 2013; 4(2): 251-253 DOI: 10.7241/ourd.20132.62
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Daifullah Al Aboud, Khalid Al Aboud
Eponyms in dermatology literature linked to Finland
Our Dermatol Online 2013; 4(2): 254-255 DOI: 10.7241/ourd.20132.63
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Piotr Brzezinski, Iffat Hassan, Anca Chiriac, Ahmad Thabit Sinjab
Dermatology Eponyms – sign –Lexicon (I)
Our Dermatol Online 2013; 4(2): 256-259 DOI: 10.7241/ourd.20132.64
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COMMENTS ON THE ARTICLES
EFFECT OF ANTIRETROVIRAL THERAPY ON SURVIVAL OF HIV/TB-INFECTED PATIENTS IN UKRAINA
Dr. Mohamed Wael Daboul (Syrian Arab Republic)
AIDS remains a monumental problem, particularly in the developing world. More than 40 million people, According to the World Health Organization are currently living with AIDS globally. Recently, many of the hematologic complications of HIV infections are less prominent because of the of highly active antiretroviral therapy (HAART) application. The declining CD4-positive lymphocyte count is associated with a progressive decline in immune function, which eventually leads to infection or neoplasia. That is why in this study, univariate analysis revealed that a baseline CD4 cell count <100/ μL was a significant predictor of mortality HR 5,6;95% CI 1,6-20,1,p=0.02). Patients who died had a mean pre-ART CD4 cell count of 77 (43-95) μL compared with 130 (65-213) μL for those who were alive. Wide spectrums of opportunistic organisms cause infections in AIDS patients, including Pneumocystis carinii, cytomegalovirus, atypical mycobacteria, Cryptococcus, histoplasmosis, and Leishmaniasis. IN this study with HIV positive individuals associated with TB, the 5 years survival rate after start of HAART estimated by the Kaplan-Meier method was 82%, which is significantly high, suggesting the importance of the association in treatment between the HAART and the anti TB regiments . Out of the 14 patients who died, the cause of death was TB in (12 cases) which is also expected due to the TB infection before the HAART treatment was initiated. In addition to that and according to this study other causes of death were cryptococal meningitis (one case) and primary CNS lymphoma (one case). In fact, Non-Hodgkin’s lymphoma (NHL) is the AIDS-defining condition in approximately 3% of HIV-infected persons, and is likely to be high grade and with a 20 percent incidence of lymphoma involvement in the central nervous system.
Reference
Mohammed Wael Daboul: Characteristics of white blood cells. Lambert Academic. Publishing 2013
A STUDY ON TINEA CAPITIS IN THE PRE SCHOOL AND SCHOOL GOING CHILDREN
Prof. Roberto Arenas (Mexico)
Interesting paper showing the epidemiological local data of tinea capitis caused frequently by T. violaceum. By the way we have in America mainly T. tonsurans and M. canis and now we are observing the emergence of M. audouinii in the Caribbean Islands.
Dr. Simon Chihanga (Botswana)
It’s a good study, but I think some of the main issues in the aim of the study have not been highlighted in the methodology, the issue of period when the study was done for one to conclude on the seasonality is not coming out. I also want to know how the sample size was determined it appears small. It also appears like most of the key results are appearing in the discussion section. The discussion section also is not making much reference to other studies in the same area what was found.
Dr. Manuel Valdebran (Dominican Republic)
Tinnea capitis an entity almost exclusively seen in children, rarely seen after puberty probably because of pH changes in scalp as well as the increase of fatty acids, conferring a fungiestatic protection [1,2].
Several factors such as hair phenotype, tropical climate, overcrowding conditions and low income have been associated with the development of tinea capitis. There are reports where fungal spores have been isolated from hair trimmers, hair combs, hats, caps and theater seats, where the spores can survive for a long time contributing to the dissemination of this entity [3,4]. Contact with other infected children at school seems to be a major independent factor in the rapid dissemination of tinea capitis [5].
Of the more than 40 species of dermatophytes previously identified, only about 12 are common causes of human infection [6]. As commented by the authors causative dermatophytes varies widely according to the different geographic areas.
In the United States before 1950 it was Microsporum audouinii the agent responsible for most of the outbreaks of tinea capitis however nowadays this organism has practically disappeared and largely replaced by Trichophyton tonsurans [7].
In Mexico researchers have reported M. canis followed by T. tonsurans as the major etiologic agents being the non-inflammatory form of the disease the most prevalent [1].
In Puerto Rico two thirds of the cases are caused by T. tonsurans and one third by M. canis.
In the Dominican Republic tinnea capitis is a public health issue, it represents 14% of all the mycosis seen in our mycology laboratory. From 1966 to 1972 M. audouinii represented 76% of the etiologic agents followed by T. ronsurans and M. canis. From 1972 to nowadays M. canis has been the predominant causal agent. However T. tonsurans has increased its prevalence in the last years being now the most common cause of tinea capitis in rural areas [5]. Similar of what is happening in other Caribbean areas such as Haiti, Puerto Rico and Jamaica [8].
In Europe the most prevalent etiological agents are M. canis, T. tonsurans, T. violaceum, T. verrucosum and T. soudanense [6]. Italy and Holland have reported an increased incidence of cases caused by M. audouinii and T. violaceum as a result in an increased immigration from African countries. In Madrid, Spain, there are reports of an increase incidence of T. tonsurans a similar phenomenon of what has happened in the US [1,6].
It is very interesting how this study reveals the prevalence of T. violaceum as the most common dermatophyte isolated, not so common in the West. Also it catches our eye the elevated prevalence of inflammatory tinnea capitis caused by the anthropophilic T. violaceum.
It will be interesting how in the future all these studies will be complemented with molecular epidemiological research. Congratulations to the group.
References
1. Rebollo N, Lopez-Barcenas AP, Arenas R: Tiña de la cabeza. Revisión. Actas dermatosifilogr. 2008;99:91-100.
2. Shy R: Tinea corporis and tinea capitis. Pediatr Rev 28:164, 2007.
3. Panasiti V, Devirgiliis V, Borroni RG, Mancini M, Curzio M, Rossi M, et al: Epidemiology of dermatophytic infections in Rome, Italy: a retrospective study from 2002 to 2004. Med Mycol. 2007;45:57–60.
4. Ngwogu AC, Otokunefor TV: Epidemiology of dermatophytoses in a rural community in Eastern Nigeria and review of literature from Africa. Mycopathologia. 2007;164:149–58.
5. Espinal A, Herrera M, Sanchez-Jorge E, Isa-Isa R, Miniño M, Cruz A, Arenas R: Tiña de la cabeza en República Dominicana. Revista Dominicana de Dermatología. 2010;1:11-15.
6. Ginter-Hanselmayer G, Weger W, Ilkit M, Smolle J: Epidemiology of tinea capitis in Europe: current state and changing patterns. Mycoses. 2007;50:1439-0507.
7. Elewski BE: Tinea capitis: a current perspective. J Am Acad Dermatol. 2000;42(1 Pt 1):1–20.
8. East-Innis A, Rainford L, Dunwell P, Barrett-Robinson D, Nicholson AM: The changing pattern of Tinea capitis in Jamaica. West Indian Med J. 2006;2:85-8.
9. Raccurt C, Dorsainvil D, Boncy M, Boncy J, Auguste G: The emergence of Trichophyton tonsurans in Port-au-Prince, Haiti. Medical Mycology. 2009;47:197-200.
A STUDY ON EFFICACY OF ORAL ZINC THERAPY FOR TREATMENT OF ACRODERMATITIS ENTEROPATHICA
Ass. Prof. Nagat Sobhy Mohamad (Egypt)
This paper is very important to dermatologists to remember the disease of acrodermatitis enteropathica during their clinical practice.
Dr. Husein Husein El-Ahmed (Spain)
In this manuscript, authors present an observational analysis of oral zinc therapy in acrodermatitis enteropathica. The sample size is quite significant, considering the prevalence of this condition. Authors show up the features of the patients included in the study such as age, sex, clinical manifestations and post-treatment following-up. Images along with the work are vissually appealing and classic representation of this condition.
Dr. Sudip Parajuli (Nepal)
This study shows that Zinc is effective in Acrodermatitis enteropathica. However, I wonder if it is really necessary to perform this study as it is already known fact that Zinc is the drug of choice for the condition mentioned. The study doesnt add anything new to the treatment of the condition.
ATROPHIC TYPE OF MORPHEA PROFUNDUS : AN INDIAN EXPERIENCE
Dr Ganesh Dhavalshankh and Dr Archana Dhavalshankh (India)
We read with admiration the report by Raveendra et al. on the Atrophic type of morphea profundus in two patients from India. The diagnosis was backed up by battery of serological investigations and a good histopathological report. We wish to make two comments. Firstly, we have also came across almost four cases (three females and one male) with asymptomatic atrophy of the skin at various sites on the body. Their age group ranged from 30-50 years. The sites mainly involved were face, upper back, chest and upper arms. The skin overlying the lesions showed no induration or tenderness similar to these two cases reported by the author. Every time we tried to investigate, all four cases showed serological and histopathological findings suggestive of lupus paniculitis. Secondly, Peterson and co-workers have proposed a classification system for morphea [1]. The term morphea profunda was proposed by Person and Su in 1981 to describe generalised inflammatory sclerosis of the panniculus or fascia [2]. Looking at the incidence of morphea in India the most common variety we notice here is either plaque or linear variety. Atrophic variety of morphea profundus is really rare to see. Leelavathy Budamakuntla et al has reported extensive morphea profunda with autoantibodies and benign tumors in 2012in male patient [3].Looking at the literature available we do agree that such cases are rarely reported from India.
Readers of your prestigious journal coming across similar symptomatology in their patients should be now beaware of this rare variant of morphea profundus and might consider reporting such to the journal.
We once again congratulate the authors for their thorough academic insight to diagnose such a rare condition and for their outstanding case report.
References
1 Peterson LS, Nelson AM, Su WP: Classification of morphea (localized scleroderma) Mayo Clin Proc. 1995;70:1068–76.
2. Su WP, Person JR: Morphea profunda: A new concept and a histopathologic study of 23 cases. Am J Dermatopathol. 1981;3:251–60.
3. Budamakuntla L, Malvankar D: Extensive morphea profunda with autoantibodies and benign tumors: A rare case report. Indian Dermatol Online J. 20123:208–10.
BLASCHKOID LICHEN PLANUS IN AN ADULT KASHMIRI MALE: A RARE PRESENTATION
Prof.Sundaramoorthy Srinivasan (India)
Whenever Lichen Planus affects only certain regions of the body the name is coined according to the pattern of distribution of the lesions as linear, zosteriform, Blaschkoid, etc.,. In this reported case though the author names it as Blaschkoid Lichen planus it involves the scalp with alopecia and it does not fit in correctly for this and more appropriate term will be an evolving Graham-Little-Piccadily syndrome. Also, previous history of Herpes-Zoster in that dermatome should have been enquired and complete evaluation for diabetic status should have been done. The most acceptable patho -mechanism behind blaschkoid lichen planus is that when the lesions are confined to one dermatome it is not easy to explain unless a mosaic phenomenon is taken into consideration.
ZOSTERIFORM LICHEN PLANUS: CASE REPORT OF A RARE VARIANT OF LICHEN PLANUS
Dr Amani Tresh (Libya)
Lichen planus is a manifestation of different diseases and it can also be present with unknown causes. In his statement (There was no past history of herpes zoster or any other skin lesions ), the author concluded that herpes zoster is excluded ,however Such a manifestation can be explained either by a subclinical VZV infection or by a VZV reactivation, which is more probable. Since there were no serological tests performed. Even with histopathology there were no comment if they tested the presence of Varicella-zoster virus (VZV) intracellular antigen and for VZV DNA.
A comment about the patient hepatitis B or C status will add a beneficial point to his case report. In general this case report is nicely written.
A COLUMELLAR DEFORMITY CAUSED BY A CONGENITAL SCHWANNOMA
Prof.Sundaramoorthy Srinivasan (India)
We appreciate the successful diagnosis and treatment of this very rare case presentation.However we must look other signs of neuro fibromaincluding mental abnormalities. The cases must be on follow up on a long term basis for detecting CNS involvement. Family history of neurofibroma or Schwannomas and other developmental history looking for developmental anomalies and delays must be looked up especially in case 2. The causes of midline nasal masses can be highlighted, the reason being from a failure of embryologic separation of neuroectodermal and ectodermal tissues during the development of the nose and frontobasal region. Many such lesions may include an intracranial extension or connection. The case presentation would be much appreciated if the histopathology picture is elaborated in detail.
FACIAL SPOROTRICHOSIS IN CHILDREN FROM ENDEMIC AREA IN PERU
Dr. César Bimbi (Brasil)
Sporotrichosis is not rare here in South America, especially during periods of humid weather and temperate climate which favours saprofitic growth of S. schenkii Also with dacaying vegetable matters, like old mines, or other conditions with timbers, old and decomposed.The incubation period is question of weeks. Trauma by thorn or insect bites may also lead to new cases and this report shows many children with this treatable infection that is in fact easy to treat and cure after being quickly diagnosed.
EPONYMS IN DERMATOLOGY LITERATURE LINKED TO GENITAL SKIN DISORDERS
Prof. Uladzimir Adaskevich (Belarus)
The article contains intersting historical data on eponyms related to skin disorders of genitalia.
NAMES OF ”LINES” IN DERMATOLOGY LITERATURE
Prof. Uladzimir Adaskevich (Belarus)
The article is also well-systematized and has data on the term „lines” in dermatology.
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