current issue2013.4

since 11.October 2013

 

C O N T E N T S   4.2013

 

 

 

 

COMMENTS ON THE ARTICLES


ORIGINAL ARTICLES


Nagat Sobhy Mohamad
Trace elements homeostatic imbalance in mild and severe psoriasis: a new insight in biomarker diagnostic value for psoriasis

      Our Dermatol Online 2013; 4(4): 449-452          DOI: 10.7241/ourd.20134.115

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Mariusz Jaworski
Relationship between health behaviors and quality of life on the one hand and satisfaction with health condition on the other hand in patients with psoriasis

      Our Dermatol Online 2013; 4(4): 453-457          DOI: 10.7241/ourd.20134.116

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Tejinder Kaur, Alpna Thakur, Kritika Pandey, Suresh Kumar Malhotra, Karan Jit Pal Singh Puri
Cutaneous TB profile in North West Punjab, India: a retrospective data analysis

      Our Dermatol Online 2013; 4(4): 458-461          DOI: 10.7241/ourd.20134.117

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Comment by: Dr Elena Chiticariu MD PhD, Dr Anca Chiriac MD PhD, Prof. Caius Solovan

      Our Dermatol Online 2013; 4(4): 462

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Nagat Sobhy Mohamad, Fayrouz Badran, Esraa Yakout
Evaluation of the efficacy of a combination – measles, mumps and rubella vaccine in the treatment of plantar warts

      Our Dermatol Online 2013; 4(4): 463-467          DOI: 10.7241/ourd.20134.118

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Ossama Hussein Roshdy, Nagat Sobhy Mohammad, Eman S. Kamha, Marwa Omar
Genetic analysis of 5 α reductase type 2 enzyme in relation to oxidative stress in cases of androgenetic alopecia in a sample of egyptian population

      Our Dermatol Online 2013; 4(4): 468-474          DOI: 10.7241/ourd.20134.119

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Comment by: Dr Luna Tanrikulu

      Our Dermatol Online 2013; 4(4): 475

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Ana Maria Abreu Velez, Juliana Calle Isaza, Michael S. Howard
Cyclo-oxygenase 2 is present in the majority of lesional skin from patients with autoinmune blistering diseases

      Our Dermatol Online 2013; 4(4): 476-478          DOI: 10.7241/ourd.20134.120

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Fatou Barro/Traoré, Boukary Diallo, Patrice Tapsoba, Jean-Baptiste Andonaba, Moussa Kéré, Pascal Niamba, Adama Traoré
La pellagre: aspects épidémiologiques et cliniques dans la Région Ouest du Burkina Faso 
Pellagra: epidemiological and clinical features in the western region of Burkina Faso

      Our Dermatol Online 2013; 4(4): 479-483          DOI: 10.7241/ourd.20134.121

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CASE REPORTS


Hisashi Tamiya, Hiromi Kobayashi, Kaori Hoshi, Yui Horiguchi, Kurooka Sadahiro, Akiko Naruse, Shigeto Yanagihara, Daisuke Tsuruta
Neutrophilic myositis associated with pyoderma gangrenosum in a break-dancer

      Our Dermatol Online 2013; 4(4): 484-486          DOI: 10.7241/ourd.20134.122

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Comment by: Ass. Prof. Małgorzata Sokołowska-Wojdyło

      Our Dermatol Online 2013; 4(4): 487

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Taeko Nakamura-Wakatsuki, Toshiyuki Yamamoto
Eruptive pigmented patches in a patient with HIV infection under HAART

      Our Dermatol Online 2013; 4(4): 488-489        DOI: 10.7241/ourd.20134.123

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Faida Ajili, Wafa Garbouj, Najeh Boussetta, Janet Laabidi, Nadia Ben Abdelhafidh, Bassem Louzir, Salah Othmani
Werner Syndrome: A new case report

      Our Dermatol Online 2013; 4(4): 490-492          DOI: 10.7241/ourd.20134.124

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Rahul Shetty, Aashish Sashidharan, Elvino Barreto, Kingsly M Paul
Varied Malignant presentations in a single case of xeroderma pigmentos

      Our Dermatol Online 2013; 4(4): 493-495          DOI: 10.7241/ourd.20134.125

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Khalid Al Aboud, Daifullah Al Aboud
Autosomal Recessive Total Congenital Anonychia, in a Saudi family

      Our Dermatol Online 2013; 4(4): 496-497          DOI: 10.7241/ourd.20134.126

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Koppada Rajasekhar, Anaparthy Usharani, Nirupama Padmaja Bondili, Ratna Harika Dusi, Perala Balamurali Krishna
A case of subcutaneous phaeohyphomycosis caused by Exserohilum species in an immunocompromised patient
      Our Dermatol Online 2013; 4(4): 498-500          DOI: 10.7241/ourd.20134.127

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Maria Bibiana Leroux
Importance of the trichoscopy in scalp dysesthesia

      Our Dermatol Online 2013; 4(4): 501-502          DOI: 10.7241/ourd.20134.128

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Alicja Rustowska, Aleksandra Wilkowska, Roman Nowicki
Iatrogenic Cushing syndrome due to topical glicocorticosteroid therapy

      Our Dermatol Online 2013; 4(4): 503-505          DOI: 10.7241/ourd.20134.129

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Taeko Nakamura-Wakatsuki, Toshiyuki Yamamoto
Cutaneous myxoid cyst on the sclerotic finger in a patient with diffuse systemic sclerosis

      Our Dermatol Online 2013; 4(4): 506-507          DOI: 10.7241/ourd.20134.130

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Faida Ajili, Hajer Ben Mansour, Héla Ghedira, Sami Zriba, Leila Metoui, Imen Gharsallah, Nadia Ben Abdelhafidh, Bassem Louzir, Fehmi M'sadak, Salah Othmani
Digital ischemia due to Systemic Sclerosis associated to Essential Thrombocythemia: A case report

      Our Dermatol Online 2013; 4(4): 508-510          DOI: 10.7241/ourd.20134.131

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Ana Maria Abreu Velez, Vickie M. Brown, Michael S. Howard
A transient drug induced lupus erythematosus – like allergic drug reaction with multiple antibodies

      Our Dermatol Online 2013; 4(4): 511-513         DOI: 10.7241/ourd.20134.132

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Ana Maria Abreu Velez, Garin Barth, Michael S. Howard
Thrombomodulin overexpression surrounding a subepidermal bullous allergic drug eruption

      Our Dermatol Online 2013; 4(4): 514-516          DOI: 10.7241/ourd.20134.133

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Liz Lezcano, Beatriz Di Martino Ortiz, Mirtha Rodríguez Masi, Oilda Knopfelmacher, Lourdes Bolla de Lezcano
Necrolisis epidermica toxica. Descripcion de dos casos. Erupción cutánea severa producida por fármacos comunes
Toxical epidermal necrolysis. Report of two cases. Severe skin rash caused by common drugs

      Our Dermatol Online 2013; 4(4): 517-521          DOI: 10.7241/ourd.20134.134

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REVIEW ARTICLES


Abdulghani Mohamed Alsamarai, Zainab Khalil Mohamed Aljumaili
Seroepidemiology of Toxoplasma, Rubella, Cytomegalovirus and Herpes Simplex Virus -2 in Women with Bad Obstetric History. PART I: Toxoplasma and Rubella infections

      Our Dermatol Online 2013; 4(4): 522-535          DOI: 10.7241/ourd.20134.135

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Abdulghani Mohamed Alsamarai, Zainab Khalil Mohamed Aljumaili
Seroepidemiology of Toxoplasma, Rubella, Cytomegalovirus and Herpes Simplex Virus -2 in Women with Bad Obstetric History. PART II. Cytomegalovirus and Herpes Simplex Virus Infections

      Our Dermatol Online 2013; 4(4): 536-544          DOI: 10.7241/ourd.20134.136

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SHORT REPORT


Neerja Puri, Asha Puri
A study on contact dermatitis to hair dye and henna

      Our Dermatol Online 2013; 4(4): 545-548          DOI: 10.7241/ourd.20134.137

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CLINICAL IMAGES


Patricia Chang
 Ungual Dyschromia

      Our Dermatol Online 2013; 4(4): 549-552          DOI: 10.7241/ourd.20134.138

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Patricia Chang, Gylari Calderón
Pediculosis Capitis

      Our Dermatol Online 2013; 4(4): 553-554          DOI: 10.7241/ourd.20134.139

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Patricia Chang, Mónica Vanesa Vásquez Acajabón
Red Lunula

      Our Dermatol Online 2013; 4(4): 555-556          DOI: 10.7241/ourd.20134.140

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LETTER TO THE EDITOR


Ilkay Bozkurt
Splinter Hemorrhage as a Side Effect of Ciprofloxacin

      Our Dermatol Online 2013; 4(4): 557-558             DOI: 10.7241/ourd.20134.141

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HISTORICAL ARTICLES


Khalid Al Aboud, Daifullah Al Aboud
Eponyms linked to vaccines and its reactions

      Our Dermatol Online 2013; 4(4): 559-563          DOI: 10.7241/ourd.20134.142

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KKhalid Al Aboud, Ahmad Al Aboud
Eponyms in the dermatology literature linked to ''Bodies'', seen in Skin biopsies

      Our Dermatol Online 2013; 4(4): 564-568          DOI: 10.7241/ourd.20134.143

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Khalid Al Aboud, Ahmad Al Aboud
Eponyms in the dermatology literature linked to Stains used in Skin biopsies

      Our Dermatol Online 2013; 4(4): 569-572          DOI: 10.7241/ourd.20134.144

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Ahmad Al Aboud, Khalid Al Aboud
Eponyms in the dermatology literature linked to Palmo-Plantar Keratoderma

      Our Dermatol Online 2013; 4(4): 573-578         DOI: 10.7241/ourd.20134.145

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Khalid Al Aboud, Ahmad Al Aboud
Eponyms linked to ''signs'' in the dermatology literature

      Our Dermatol Online 2013; 4(4): 579-581         DOI: 10.7241/ourd.20134.146

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COMMENTS ON THE ARTICLES

TRACE ELEMENTS HOMEOSTATIC IMBALANCE IN MILD AND SEVERE PSORIASIS: A NEW INSIGHT IN BIOMARKER DIAGNOSTIC VALUE FOR  PSORIASIS


Dr. Manuel Valdebran (Dominican Republic)
It is interesting how certain trace elemets can be altered in moderate-severe psoriasis. It would be interesting to perform further research focused on calcium, phosphorous, zinc and copper and its relationship with psoriasis develpment, severity and how its correction affects in the progression of the disease. 
 
 
 
 
RELATIONSHIP BETWEEN HEALTH BEHAVIORS AND QUALITY OF LIFE ON THE ONE HAND AND SATISFACTION WITH HEALTH CONDITION ON THE OTHER HAND IN PATIENTS WITH PSORIASIS
 
Dr Elena Chiticariu, MD PhD, Dr Anca Chiriac, MD PhD, Prof. Caius Solovan (Romania)
Psoriasis has complex psychological, medical, and social implication. Although the literature regarding the quality of life in this disease is quite extensive, it is an interesting approach to assess the relationship between behaviours and quality of life, satisfaction, and severity. Jaworski M nicely illustrated here the need to promote health behaviours in psoriatic patients. Among them, diet has a key role. 
This study demonstrated that the general health behaviours, positive mental attitude, and health practices don’t differ between psoriatic patients and controls, but there was a significant difference regarding the health-promoting eating behaviour. Although an important limitation is the small size of the sample (61/60), the article is clear and methods are properly chosen. This is important because nutrition can interact with psoriatic lesions as follows: the lesions may be improved by low-calorie diets, fatty acids modulate proin?ammatory cytokines, the intake of antioxidants may lower the oxidative stress found in psoriasis, and vitamins (D and B12) could have positive effects on psoriatic skin [1].
The study also showed differences regarding the body mass index. It is not a novelty. Beyond the fact that the dietary composition could influence the skin changes in psoriasis, weight gain was reported as a risk factor for developing the disease [2]. Furthermore, there have been established genetic and pathogenic links between psoriasis and obesity. Eating behaviours and obesity add to the risk of metabolic syndrome reported in patients with psoriasis [3]. 

References:
1. Wolters M: Diet and psoriasis: experimental data and clinical evidence. Br J Dermatol. 2005;153:706-14.
2. Setty AR, Curhan G, Choi HK: Obesity, waist circumference, weight change, and the risk of psoriasis in women: Nurses’ Health Study II. Arch Intern Med. 2007;167:1670–167.
3. Armstrong AW, Harskamp CT, Armstrong EJ: Psoriasis and metabolic syndrome: a systematic review and meta-analysis of observational studies. J Am Acad Dermatol. 2013;68:654-62.
 
 
Ass. Prof. Constantin Caruntu, MD PhD (Romania)
The study addresses a topic of interest for both clinicians and researchers. Its objective was to analyze the frequency of health behaviors in patients with psoriasis and their impact on quality of life.

The evaluation is performed on relatively large groups of psoriasis patients and control subjects. However in future studies assessing possible differences between men and women could provide interesting results regarding health behaviours. Also, even if the subjects in the control group had no diagnosed psoriasis would be very helpful the evaluation of any other disorders and their possible impact on quality of life and health behaviours.
The study suggests the existence of certain connections between health behaviours and evolution of psoriasis lesions. Also, an interesting aspect of the study is the comparative presentation of results obtained from patients with psoriasis and those obtained from patients with severe chronic diseases.
The study highlights the importance of a complex approach of patients with psoriasis, suggesting the need for more nutrition education directed to patients with psoriasis. It is also emphasized the bidirectional relationship between stress and psoriasis, highlighting the importance of psychological support for these patients.
An important aspect that must be considered in future studies is the use of validated tools, widely used in scientific literature to assess the quality of life of patients with psoriasis, such as Dermatology Life Quality Index (DLQI) and Psoriasis Disability Index (PDI). Also, is available the most widely used tool for the assessment of severity of psoriasis: Psoriasis Area and Severity Index (PASI). On the other hand, the instrument used to assess health-related behaviors is characterized by satisfactory reliability and validity parameters and could be useful for other researchers in future studies.

In conclusion, the article provides interesting new information and is a starting point for further studies on the relationship between health behaviors and psoriasis.

 
 
 
Dr. Manuel Valdebran (Dominican Republic)

It is a very interesting article that should remind us the inflammatory nature of psoriasis and its shared pathophysiologic pathways with metabolic syndrome.
Adipose tissue is capable of secreting hormones and cytokines such as leptin, adiponectin which are implicated in psoriasis and metabolic syndrome. By the other hand physical activity independent of fat loss could have antiinflammatory effects. In fact certain authors show that TNF-α, IL6, INF-?, ICAM-1 and VCAM-1 may be lowered by physical activity [1]
There is a need to evaluate well-designed active life-style modifying interventions in psoriasis such as in the aspects of physical activity and eating habits. 

Reference:
1.Wilson PB, Bohjanen KA, Ingraham AS, Leon AS: Psoriasis and physical activity: a review. J Eur Acad Dermatol Venereol. 2012;26:1345-53.
 
 
Dr. Françoise Raverdy (France)

I’m writing a comment of the present article as I have been involved in the development of clothing and garments specially designed to calm down rashes of psoriasis called DOODERM clothing.

Even if “schools” and structures made for patients suffering from atopic dermatitis already exist today (see for instance the works of Professor Staedler from Nantes’ University Hospital and those of Professor De Raeve in Brussels), meeting places for support, care and advisement with multidisciplinary teams for people with psoriasis should be design and multiply.
The present article underlines clearly this particular point. There is a real need today for practical education in medical, nutritional and psychosocial field for psoriasis patients. Background education and dedicated advices will allow the psoriasis patients to enhance their self-esteem, their confidence and therefore they should feel better about themselves.
As the number of people suffering from psoriasis is increasing in today’s world, dedicated place for education should be think as a Public Health issue. Furthermore, the fact that psoriasis is known as a chronic disease lead us to think that remission phases could be used as right time to support patients with stress and anxiety management, healthy eating recommendations and other healthy practices, such as sport or creative activities. Everything should be done to teach psoriasis patients about the prevention behaviors that will improve their life.
For instance, to improve patient well-being, night clothes and underwear with silver fiber (with anti-inflammatory, anti-bacterial and antifungal properties) have been designed to calm down the itching, to limit or avoid the tedious use of creams and pomades. With silver fiber clothes, the patient can live normally and have a feeling of relief from persistent itching stages.
These types of products are definitively not the cure for psoriasis but they are beneficial resources that can bring comfort and well-being to patients (from kids to adults) and give them the ability to cope with the disease itself. Doctors, therapists, nutritionists, laboratories and industrial firms should join their efforts to help and support people with psoriasis.
The article conclude that a more important survey should be led to cross the effects of healthy eating habits with the evolution of the patient’s skin. However the survey should not be limited to the nutritional education but also take in account the psychological care. No doubt that this type of survey would beneficiate to be lead internationally in order to better understand this psoriasis epidemiology. 

 
 
CUTANEOUS TB PROFILE IN NORTH WEST PUNJAB, INDIA: A RETROSPECTIVE DATA ANALYSIS
 
Dr. Neerja Puri (India)
The article is nicely written. the article clearly shows that the incidence of cutaneous tuberculosis is on the decline because of the effectivity of revised national tuberculosis control programme in india. The clinical spectrum of various clinical types of tb is well described, though the histopathological correlation needs to be a bit elaborated. overall good work done.
 
 
Prof. Roberto Arenas (Mexico)
In many countries tuberculosis cutis as this paper mention is diagnosed by the histopathological correlation. Fortunatly incidence is decreasing thanks to National Programs for early diagnosis and treatment.
 
 
Dr. Haider Abdul-Lateef Mousa (Iraq)
Well organized article which describes the prevalence of cutaneous TB within dermatology patients in India. However, from the study data, this appears to be prevalence 0.02% (not incidence) among dermatology patients. Therefore, it does not reveal the incidence or prevalence among whole population. The study gives valuable clues for clinical presentations and methods of diagnosis. 
 
Dr. Max Carlos Ramírez Soto (Peru)
Is a very interesting study, however, no mention in the method that performs statistical analysis. Furthermore, the methodology states that data recovered and acid alcohol stain resistant, but the results do not present this evidence are also important. In the skin lesions is necessary to know the time evolution for the differential diagnosis against other infections. Congratulations to the authors for this interesting study.

 
 
 
GENETIC ANALYSIS OF 5 Α REDUCTASE TYPE 2 ENZYME IN RELATION TO OXIDATIVE STRESS IN CASES OF ANDROGENETIC ALOPECIA IN A SAMPLE OF EGYPTIAN POPULATION
 
Dr. Rania Mounir Abdel Hay (Egypt)
This is an important issue that can the raise the possible use of antioxidants as an adjuvant treatment in AGA.
 
 
 
CYCLO-OXYGENASE 2 IS PRESENT IN THE MAJORITY OF LESIONAL SKIN FROM PATIENTS WITH AUTOINMUNE BLISTERING DISEASES
 
Dr. Rania Mounir Abdel Hay (Egypt)
This is an interesting study discussing the role of an important marker of innate immune system that can have an implication on the future treatment plan for these autoimmune diseases. As the author mentioned, it would be great to do further larger study for confirmationon.

 
 
 
 
LA PELLAGRE: ASPECTS ÉPIDÉMIOLOGIQUES ET CLINIQUES DANS LA RÉGION OUEST DU BURKINA FASO 
PELLAGRA: EPIDEMIOLOGICAL AND CLINICAL FEATURES IN THE WESTERN REGION OF BURKINA FASO

 
Prof. Roberto Arenas (Mexico)
Pellagra still exist? I have read this question 35 years ago (Br J Derm 1977;96(1):99-106). Now in 2013, this paper show us that it still exist in rural and urban zones in Burkina Faso. The authors report 223 cases in 7 year, mainly affecting females and presenting severe ulcerated lesions.
 
 
 
NEUTROPHILIC MYOSITIS ASSOCIATED WITH PYODERMA GANGRENOSUM IN A BREAK-DANCER
 
 
QUESTION 
Alin Tatu, MD PhD (Romania)
How did you think that  trauma had an  influence for the neutrophilic disease-do you think that is a vascular repetitive trauma,or the metabolits or cytokines are involved?
 
ANSWER
Hisashi Tamiya, Hiromi Kobayashi, Kaori Hoshi, Yui Horiguchi, Kurooka Sadahiro, Akiko Naruse, Shigeto Yanagihara, Daisuke Tsuruta (Japan)
First, I think a possibility of involvement of cytokines, activating neutrophils.
Indeed, exhaused exercise induces neutrophil and cytokine accumulation, mainly such as IL-6, in damaged muscle.
So, in this case, compulsive exercise may be a trigger an abnormal, neutrophilic inflammatory reaction with high cytokines level, such as IL-6, in the muscle tissue.
However, I cannot deny allergic reaction to metabolites of necrotic tissue of muscle by traumatic injury. 

 
 
Prof. Uwe Wollina (Germany)
Pyoderma gangrenosum (PG) is one of the most classical examples of neutrophilic dermatoses. It has been shown, that PG is associated with a significant amount of comorbidities [1] with anemia, endocrine disorders, and malignancies as the leading ones.
Extracutaneous manifestations of PG are rare. Hepatitis, pneumonitis, osteitis, gall bladder, and myositis are known. Tamiya et al. report on a case of PG-associated neutrophilic myositis probably induced by mechanical forces during break-dance. This case is unique since the PG does not present with painful rapidly enlarging livid ulcers [2].
The myositis without any doubt demonstrated the typical histopathological findings of neutrophilic myositis and responded well to systemic corticosteroids. Why did the boy not develop ulcers before although difficulties with his right knee were observed several times? Why only the right and not both knees? Not all questions can be answered easily, since our knowledge of PG is still limited.
Based on this interesting observation compulsive exercise has to be included in the long list of trigger factors of PG.
 
References:
1. Al Ghazal P, Herberger K, Schaller J, Strölin A, Hoff N-P, Goerge T, et al: Associated factors and comorbidities in patients with pyoderma gangrenosum in Germany: a retrospective multicentric analysis in 259 patients. Orphanet J Rare Dis. 2013;8:136.
2. Wollina U: Pyoderma gangrenosum – a review. Orphanet J Rare Dis. 2007;2:19.
 
 
Ass. Prof. Viktoryia Kazlouskaya (Belarus)
The article describes another condition from the spectrum of neutrophilic dermatoses. The neutrophilic myositis and pyoderma gangrenosum are indistinguishable histopathologically and differ only by location. Obviously, they represent the spectrum of changes of the same process. Interestingly, the condition presented by the authors involves the skin and muscle which raises a question where it appeared first? The case may represent an unusual presentation of pyoderma gangrenosum with a muscle involvement. Al Ghazal et al (2012) in his article published in the Journal of German Society of Dermatology mention minor trauma as the causative agent of pyoderma gangrenosum developement. In that sense, active breakdancing may be classified as such. Some potential new co-factors (metabolic syndrome, anemia and endocrine diseases) were also described. A further follow up of the patient is still needed to fully exclude the underlying conditions. 

 
 
 
WERNER SYNDROME: A NEW CASE REPORT
 
Prof. Uwe Wollina (Germany)
Werner syndrome (WN) is one of the archetypes of premature aging syndromes. It is associated with abnormal hair growth, ateriosclerosis, and delayed healing and nonresponse to topical platelet-derive growth factor PDGF – BB [1].

The WRN gene (also called RECQL2 or REQ3) was first cloned in 1996. Since then numerous mutations have been identified. The most penetrant phenotype of WS is bilateral ocular cataracts [2].
The new case by Faida Ajili et al demonstrates several clincial signs suggestive of WN like bird face, alopecia and bilateral ocular cataract. Unfortunately, no WRN gene mutation analysis has been undertaken to confirm the diagnosis on the molecular level. International Registry of Werner syndrome (www.wernersyndrome.org) provides gene analysis.
Patients with WN need an interdisciplinary approach, since various organs become affected. There is no cure for this rare disease but a multidisciplinary task force may provide support that enables a better quality of life.
 
References:
1. Wollina U, Gruner M, Koch A, Köstler E, Hubl W, Hanson NB, et al: Topical PDGF-BB results in limited healing in a patient with Werner's syndrome and chronic leg ulcers. J Wound Care. 2004;13:415-6.

2. Huang S, Lee L, Hanson NB, Lenaerts C, Hoehn H, Poot M, et al: The spectrum of WRN mutations in Werner syndrome patients. Hum Mutat. 2006;27:558-67.

 
 
 
IMPORTANCE OF TRICHOSCOPY IN SCALP DISESTESIA
 
Dr Alin Tatu (Romania)
The article is simmple  and precise. The trichoscopy helps the diagnosis of  the scalp disorder observing  the skin, scales and the hair. The absence of the blood excludes trichotilomania!
 
 
Dr Emina Kasumagic-Halilovic, MD, PhD (Bosnia and Herzegovina)
This is an interesting article that contributes a better understanding of importance of the trichoscopy in scalp diseases. Videodermoscopy of hair and scalp (trichoscopy) is a modern, non-invasive technique, which is well accepted by both, dermatologists and patients. Structures which may be visualised by trichoscopy include hair shafts, hair follicle openings, the perifollicular epidermis, and cutaneous microvasculature. In the last few years many studies have been published in this field. This case is reported to highlight the trichoscopic features of scalp dysesthesia and how trichoscopy can help the clinician for better than the other methods in the diagnosis of atypical cases of scalp diseases.

 
 
 
 IATROGENIC CUSHING SYNDROME DUE TO TOPICAL GLICOCORTICOSTEROID THERAPY
 
Dr Nermina Ovčina-Kurtovic, MD, MA (Bosnia and Herzegovina)
This case report is very interesting. In everyday dermatological practice rarely we can see this expressed adverse effects of local corticosteroid therapy. This case study demonstrates that always when using local glucocorticosteroids in the treatment of children, we must to explain parents the possibility of serious side effects, if the treatment is applied uncontrollably.
 
 
 
 A TRANSIENT DRUG INDUCED LUPUS ERYTHEMATOSUS – LIKE ALLERGIC DRUG REACTION WITH MULTIPLE ANTIBODIES
 
Dr. Cesar Bimbi (Brasil)
How many of the cases labeled as Systemic Lupus Erythematosus are in fact drug-reactions? We have to consider that few of us really waste the necessary amount of time asking our patients about pills usually taken.. and also that Drug Induced Lupus are more prevalent in older age groups that is when people " forget" the many remedies ingested. The variety of pills linked to DIL ( anticonvulsant agents, antithyroid, sulfas,beta-blockers, lithium ..- although those mentioned by the authors are the main ones ) are another important thing. And the clinical pictures are almost the same. The lab findings showed here by the authors are important itens to consider , in order to advise the withdrawal the drug and led the patient to cure.virus.
 
 
 
 
EPONYMS IN THE DERMATOLOGY LITERATURE LINKED TO PALMO-PLANTAR KERATODERMA
 
Viktoryia Kazlouskaya, MD, PhD (Belarus)
"If you don`t know your past, you don`t know your future!" Otto von Habsburg. Thank you for this nice historical review and in general for the cycle of articles on eponyms. That is excellent idea to have them all organized in tables and classified by topics. 


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