2013.1

since 02. January 2013

 

C O N T E N T S   1.2013

 

 

 

 

COMMENTS ON THE ARTICLES


ORIGINAL ARTICLES


Nagat Sobhy, Ali Atia, Mahmoud Elramly
Some modifications in transplantation of autologus non -cultured melanocytes-keratinocytes suspension in treatment of segmental and focal vitiligo (Egyptian Experience in Alexandria University)

      Our Dermatol Online 2013; 4(1): 5-10          DOI: 10.7241/ourd.20131.01

[abstract-English] , [article in English],   [PDF][HTML]

Rania M. Abdel Hay, Noha F. Ibrahim, Dina Metwally, Laila A. Rashed
The role of interleukin-1ß and interleukin-33 in atopic dermatitis

      Our Dermatol Online 2013; 4(1): 11-14          DOI: 10.7241/ourd.20131.02

[abstract-English] , [article in English],    [PDF], [HTML]

 

Comment by: Ass. Prof. Miloš Jeseňák

      Our Dermatol Online 2013; 4(1): 15          DOI: 10.7241/ourd.20131.02.1

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Neerja Puri, B B Mahajan, Samarjeet Kaur Sandhu
Clinical evaluation of different therapeutic modalities in psoriasis by Pasi score

      Our Dermatol Online 2013; 4(1): 16-22          DOI: 10.7241/ourd.20131.03

[abstract-English] , [article in English],   [PDF][HTML]

 

Comment by: Hisayoshi Imanishi, MD, PhD, Daisuke Tsuruta, MD, PhD

      Our Dermatol Online 2013; 4(1): 23          DOI: 10.7241/ourd.20131.03.1

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Iffat Hassan, Taseer Bhat, Hinah Altaf, Farah Sameem, Qazi Masood
Role of oral zinc sulphate in warts-a placebo controlled,single-blinded study

      Our Dermatol Online 2013; 4(1): 24-27          DOI: 10.7241/ourd.20131.04

[abstract-English] , [article in English],   [PDF], [HTML]

Gabriela Martínez Braga, Rosalba Riveros, Beatriz Di Martino Ortiz, Julio Recalde, Lourdes Bolla
Dermatoscopía: contribución como método para definir márgenes quirúrgicos de carcinomas basocelulares de cara, cuello y tronco
      Our Dermatol Online 2013; 4(1): 28-31          DOI: 10.7241/ourd.20131.05

[abstract-Spanish, English] , [article in Spanish],   [PDF], [HTML]

Ashutosh Talwar, Neerja Puri
A study on the surgical treatment of ingrowing toe nail with nail excision with chemical matricectomy versus nail excision alone
      Our Dermatol Online 2013; 4(1): 32-34          DOI: 10.7241/ourd.20131.06

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Ajith P. Kannangara, Alan B. Fleischer, Gil Yosipovitch
The Sparing Phenomenon. A case series of the inverse Koebner and related phenomena

      Our Dermatol Online 2013; 4(1): 35-39          DOI: 10.7241/ourd.20131.07

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Nagat Sobhy, Hala Aly, Adel El Shafee, Marwa El Deeb
Evaluation of the effect of injection of dutasteride as mesotherapeutic tool in treatment of androgenetic alopecia in males

      Our Dermatol Online 2013; 4(1): 40-45          DOI: 10.7241/ourd.20131.08

[abstract-English] , [article in English],   [PDF], [HTML]

Mohammed Wael Daboul
Toward an approach for cutaneous leishmania treatment
      Our Dermatol Online 2013; 4(1): 46-54          DOI: 10.7241/ourd.20131.09

[abstract-English] , [article in English],   [PDF], [HTML]

 

Comment by: Prof. Mehmet Doganay

      Our Dermatol Online 2013; 4(1): 55          DOI: 10.7241/ourd.20131.09.1

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Neerja Puri, Asha Puri
A study on dermatoses of pregnancy
      Our Dermatol Online 2013; 4(1): 56-60          DOI: 10.7241/ourd.20131.10

[abstract-English] , [article in English],   [PDF], [HTML]

Piotr BrzezinskiKarol Kołatka, Ahmad Thabit Sinjab, Bury Marta
Piezogenic pedal nodules of young children and their parents

      Our Dermatol Online 2013; 4(1): 61-63          DOI: 10.7241/ourd.20131.11

[abstract-English] , [article in English],   [PDF], [HTML]


CASE REPORTS


Ana Maria Abreu Velez, Billie L. Jackson, Katya Lisette Velasquez Cantillo, Andersson Rafael, Benavides Alvarez, Michael S. Howard
Merkel cell carcinoma versus metastatic small cell primary bronchogenic carcinoma

      Our Dermatol Online 2013; 4(1): 64-71          DOI: 10.7241/ourd.20131.12

[abstract-English] , [article in English],   [PDF], [HTML]

Geetha Vasudevan, Bikash Singhania, Archana Shivamurthy
Myxoid Dermatofibrosarcoma Protuberans of the vulva with myoid nodules: Clinicopathologic and Immunohistochemical study of a case

      Our Dermatol Online 2013; 4(1): 72-74         DOI: 10.7241/ourd.20131.13

[abstract-English] , [article in English],    [PDF], [HTML]

Rahul Shetty, Shashank Lamba, Archana Gulur, Sapna Patel, Ashish Kumar Gupta
Carcinoma in cutaneous Lichen Planus

      Our Dermatol Online 2013; 4(1): 75-77          DOI: 10.7241/ourd.20131.14

[abstract-Engli sh] , [article in English],   [PDF], [HTML]

Falguni Nag, Arghyaprasun Ghosh, Gobinda Chatterjee, Nidhi Choudhary
Lichen planus pigmentosus: two atypical presentation

      Our Dermatol Online 2013; 4(1): 78-79          DOI: 10.7241/ourd.20131.15

[abstract-English] , [article in English],   [PDF], [HTML] 

Taeko Nakamura-Wakatsuki, Toshiyuki Yamamoto
Sarcoidosis presenting erythema nodosum-like lesions: report of two cases

      Our Dermatol Online 2013; 4(1): 80-82          DOI: 10.7241/ourd.20131.16

[abstract-English] , [article in English],   [PDF], [HTML]

Ana Maria Abreu Velez, Vickie M. Brown, Lyndsay Shipp, Bruce R. Smoller, Michael S. Howard
N-traps and C-ancas in a lupus erythematosus-scleroderma overlap syndrome with vasculitis and panniculitis
      Our Dermatol Online 2013; 4(1): 83-86          DOI: 10.7241/ourd.20131.17

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Deeptara Pathak Thapa, Anil Kumar Jha, Sujata Pudasaini, Chandani Kharel, Shristi Shrestha
Genital Hailey- Hailey disease: a case report

      Our Dermatol Online 2013; 4(1): 87-88          DOI: 10.7241/ourd.20131.18

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Anagha Ramesh Babu, Metikurke Vijayashankar
Terra Firma-forme Dermatosis

      Our Dermatol Online 2013; 4(1): 89-90          DOI: 10.7241/ourd.20131.19

[abstract-English] , [article in English],   [PDF], [HTML]

Ana Maria Abreu Velez, Michael S. Howard
Neural reactivity detected by immunofluorescence in a patient with a localized blistering disease

      Our Dermatol Online 2013; 4(1): 91-94          DOI: 10.7241/ourd.20131.20

[abstract-English] , [article in English],   [PDF], [HTML]


OPINION ARTICLE


Neerja Puri, Ashutosh Talwar
Litigation against dermatosurgeons and cosmetologists and consumer protection act

      Our Dermatol Online 2013; 4(1): 95-97          DOI: 10.7241/ourd.20131.21

[abstract-English] , [article in English],   [PDF], [HTML]


CLINICAL IMAGES


Max Carlos Ramírez Soto
Seborrheic Dermatitis by Demodex folliculorum

      Our Dermatol Online 2013; 4(1): 98-100          DOI: 10.7241/ourd.20131.22

[article in English],   [PDF], [HTML] 


LETTERS TO THE EDITOR


Ramesh Y Bhat, Chaitanya Varma
Reversible hypopigmentation of hair secondary to Vitamin B12 deficiency

      Our Dermatol Online 2013; 4(1): 101-102          DOI: 10.7241/ourd.20131.23

[article in English],   [PDF], [HTML]

Anca Chiriac, Doina Mihaila, Caius Solovan, Anca E. Chiriac, Liliana Foia
Adult urticaria pigmentosa with transitory disappearance of lesions during enoxaparinum treatment

      Our Dermatol Online 2013; 4(1): 103-104          DOI: 10.7241/ourd.20131.24

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DERMATOLOGY EPONYMS


Ahmad Al Aboud
Chong Hai Tay and the syndrome which bears his name

      Our Dermatol Online 2013; 4(1): 105          DOI: 10.7241/ourd.20131.25

[article in English],   [PDF], [HTML]

Ahmad Al Aboud
Ernst Hanhart (1891-1973 ) and the syndrome which bears his name

      Our Dermatol Online 2013; 4(1): 106-107          DOI: 10.7241/ourd.20131.26

[article in English],   [PDF], [HTML]

Ahmad Al Aboud
Erich Urbach (1893-1946) and the medical eponyms which bear his name

      Our Dermatol Online 2013; 4(1): 108-109         DOI: 10.7241/ourd.20131.27

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Khalid Al Aboud, Ahmad Al Aboud
Eponyms in dermatology literature linked to Australia

      Our Dermatol Online 2013; 4(1): 110-112          DOI: 10.7241/ourd.20131.28

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Khalid Al Aboud, Ahmad Al Aboud
Eponyms in dermatology literature linked to Canada

      Our Dermatol Online 2013; 4(1): 113-116         DOI: 10.7241/ourd.20131.29

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Khalid Al Aboud, Ahmad Al Aboud
Eponyms in dermatology literature linked to Sweden

      Our Dermatol Online 2013; 4(1): 117-120          DOI: 10.7241/ourd.20131.30

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Khalid Al Aboud, Daifullah Al Aboud
Eponyms in dermatology literature linked to Switzerland

      Our Dermatol Online 2013; 4(1): 121-127          DOI: 10.7241/ourd.20131.31

[article in English],   [PDF], [HTML]

Khalid Al Aboud, Ahmad Al Aboud
The fading eponym of ''Verneuil's disease''

      Our Dermatol Online 2013; 4(1): 128-129          DOI: 10.7241/ourd.20131.32

[article in English],   [PDF], [HTML]

Piotr Brzezinski, Larissa Pessoa, Virgilio Galvão, Juan Manuel Barja Lopez, Uladzimir Petrovitch Adaskevich, Pascal A. Niamba, Miki Izumi, Kuniaki Ohara, Brian C. Harrington, Sundaramoorthy M. Srinivasan, Ahmad Thabit Sinjab, Casey M. Campbell
Dermatology Eponyms – sign –Lexicon (H)

      Our Dermatol Online 2013; 4(1): 130-143          DOI: 10.7241/ourd.20131.33

[abstract-English] , [article in English],   [PDF], [HTML]





COMMENTS ON THE ARTICLES

THE ROLE OF INTERLEUKIN-1β AND INTERLEUKIN-33 IN ATOPIC DERMATITISA


Emina Kasumagić-Halilovic, MD PhD (Bosnia and Herzegovina)
The importance of cytokines in dermatology is increasing dramatically. Recent progress in the understanding of atopic dermatitis has shown that the regulation of local and systemic cytokines play an important role in its pathogenesis. Abdel Hay and co authors presented excellent study. They found that both IL-1β and IL-33 were statistically higher in patients than in healthy individuals, and in addition, IL-33 was statistically highly detected in severe cases of atopic dermatitis. Further investigation are required to clarify the pathogenetic role and clinical significance of IL-1 and IL-33, and these findings may provide important clues to assist in the development of new therapeutic strategies for patients with atopic dermatitis. The specific blockade of cytokines or their receptors is an alternative approach for the treatment of atopic dermatitis.

Dr Manuel Valdebran (Dominican Republic)
The article refers to an interesting clinical trial that addresses the need of a tool to measure the severity of the lesions in psoriasis in order to give the most appropriate treatment or combination of treatments. Therapeutics in psoriasis is always a challenge especially in underdeveloped countries where many patients don’t have access to all the therapeutic modalities because of scarcity of specialized dermatologic facilities or because of the cost of the treatment. It is required that the dermatologist to be the most efficient as possible in the election of the treatment, therefore a good staging of the severity of the illness is needed. We also need to take into consideration the quality of life of patients living with psoriasis as a decrement in this index increases the severity of psoriasis disregard of the clinical staging of the lesions. It is always a challenge for us to do further research in this interesting and sensitive topic.
 
 
 
A STUDY ON THE SURGICAL TREATMENT OF INGROWING TOE NAIL WITH NAIL EXCISION WITH CHEMICAL MATRICECTOMY VERSUS NAIL EXCISION ALONE
 
Dr. Roni Leonardo Teixeira (Brazil)
Although this is a trivial condition, and that some how brings some discomfort to their carriers, the alternative with phenol, was effective in resolving ungueites, with very low morbidity, whichbecomes a reality in the middle of dermatologic Surgery. The follow up, it is necessary, due to the recurrence of the disease during the conventional treatment, which would add further datatreatment with phenol, and the ir long term effects.

Dr. Shahin Aghaei (Iran)
Firstly, an exsanguinating tourniquet is used to maintain a bloodless surgical field for 2 reasons: Blood is known to inactivate phenol [1]. A dry surgical field helps to facilitate contact between the matrix and the chemocauterant [2]. Secondly, both matricectomy techniques have advantages and disadvantages. It seems, according to the some prior studies, patient evaluation of cosmetic outcome was not different between the groups, but the recurrence rates were significantly higher in the group with phenolization method. This result is against to what Dr. Talwar has obtained in his study [3]. Lastly, both sodium hydroxide and phenol are effective agents giving high success rates, but sodium hydroxide causes less postoperative morbidity and provides faster recovery [4] especially that one-minute application of 10% sodium hydroxide is simple, safe, and highly effective for the treatment of ingrown nails [5]. Overall, phenol matricectomy is highly effective method which could be done in the office and has shorter off- works time than conventional surgery.

REFERENCES:
1. Ceilley RI, Collison DW: Matricectomy. J Dermatol Surg Oncol. 1992;18:728-34.
2.Clark RE, Madani S, Bettencourt MS: Nail surgery. Dermatol Clin. 1998;16:145-64.
3.Hassel JC, Hassel AJ, Löser C: Phenol chemical matricectomy is less painful, with shorter recovery times but higher recurrence rates, than surgical matricectomy: a patient's view. Dermatol Surg. 2010;36:1294-9.
4.Bostanci S, Kocyigit P, Gürgey E: Comparison of phenol and sodium hydroxide chemical matricectomies for the treatment of ingrowing toenails. Dermatol Surg. 2007;33:680-5.
5.Kocyigit P, Bostanci S, Ozdemir E, Gürgey E: Sodium hydroxide chemical matricectomy for the treatment of ingrown toenails: comparison of three different application periods. Dermatol Surg. 2005;31:744-7; discussion 747.


ROLE OF ORAL ZINC SULPHATE IN WARTS-A PLACEBO CONTROLLED, SINGLE-BLINDED STUDY
 
Dr. Husein Husein-ElAhmed (Spain)
The authors of this manuscript have focused their research in a very common dermatological condition: warts. This disease often is a challenge for dermatologists because the high rate of recurrences or absence of response in certain percentage of patients. It is uncommon to find patients in whom the classic treatments of local tissue destruction are not effective. This manuscript is very interesting and it has a great value for consultants as it showed the efficacy of oral zinc suphate in warts. The trial is well-designed and conducted, placebo-compared and it has a considerable sample size, which adds strength to the findings observed by the authors. However, it would be of interest to know the statistical tests performed in the study. Finally, this work can change the daily clinical practice of many physician as it focused on a very common condition and it showed that oral zinc sulphate can be a rationale option for those patients in whom the scarring topical treatments are contraindicated or showed no response.


DERMATOSCOPÍA: CONTRIBUCIÓN COMO MÉTODO PARA DEFINIR MÁRGENES QUIRÚRGICOS DE CARCINOMAS BASOCELULARES DE CARA, CUELLO Y TRONCO
 
Dr. Roni Leonardo Teixeira (Brazil)
Interesting study, with a certain applicability, thereby avoiding large mutilation in patients with basal cell skin tumors. Dermoscopy is a methodology that has aggregate, low cost and easy implementation.

Dr. Manuel Valdebran (Dominican Republic)
El artículo es interesante ya que enfatiza la utilidad de la dermatoscopía como herramienta útil, económica y efectiva para la prevención de recidivas en extirpaciones de carcinomas basocelulares. En los centros dermatológicos donde no sea posible realizar cirugía de Mohs, la dermatoscopía podría ser de mucha utilidad en la demarcación de márgenes quirúrgicos más precisos. El estudio destaca una reducción estadísitcamente significativa en la positividad de márgenes tomados comparado con los controles. Hubiera sido interesante conocer más específicamente sobre la variación en cuanto a extensión o reducción de los márgenes quirúrgicos cuando se usó la dermatoscopía y los hallazgos dermatoscópicos en la periferia de las lesiones. Este interesante estudio sienta un precedente para futuros estudios multicéntricos.


EVALUATION OF THE EFFECT OF INJECTION OF DUTASTERIDE AS MESOTHERAPEUTIC TOOL IN TREATMENT OF ANDROGENETIC ALOPECIA IN MALES
 
Dr Manuel Valdebran (Dominican Republic)
This controlled trial conducted by Dr. Sobhy and coworkers is very interesting. Remarkable value can be done to its novelty and contribution by offering an avenue for a new modality of treatment for androgenic alopecia. In the present study, mesotherapy with dutasteride was used alone but more research can be done comparing dutasteride in combination of other modalities of treatment. Following a safe treatment protocol considering the half-life of the drug and monitoring side effects, mesotherapy with dutasteride promise to be an effective and safer option of treatment for androgenic alopecia.



A STUDY ON DERMATOSES OF PREGNANCY AND HAVE SOME OBSERVATIONS.
 
Dr. Rukhsana Parvin (Bangladesh)
1. The highlighted areas can be written in better sentences and repeatation of the words can be avoided.
2. The width of the tables can be in shorter form.
3. In discussion section, results are repeated. These should be omitted here. There are less comparisons with the other studies.The topics are written elaborately,but actually the author should state more similar studies regarding their article,so that one can understand which dermatoses are more common or rare in pregnancy.

Ass Prof. Iffat Hassan (India)
The authors have deliberated on a very important topic which one comes across in day to day clinical practice. The article is very informative and will make an interesting reading for its readers.

Ass Prof. Rania M Abdel Hay (Egypt)
Dermatoses of pregnancy are group of disorders that can be seen by both dermatologists and obstetricians and so it is so important to know well the clinical picture and how to manage each dermatosis by both of them. It is also important to highlight the benefit of collaboration between dermatologists and obstetricians in order to achieve better maternal and fetal outcomes.



SARCOIDOSIS PRESENTING ERYTHEMA NODOSUM-LIKE LESIONS: REPORT OF TWO CASES
 
Anca Chiriac MD,PhD (Romania)
Cutaneous sarcoidosis has different manifestations that make it difficult to diagnose, it is well known and sometimes hard to accept. So clinical, histopathologic and laboratory evaluation are of great importance for a sure diagnosis and a carefull follow up of the patients. We appreciate the description made by Taeko Nakamura-Wakatsuki, Toshiyuki Yamamoto , of erythema nodosum – like eruption as a cutaneous signal for sarcoidosis. It is a rare aspect along with others, presented recently in the literature (for example: scar sarcoidosis [1], initial scarring alopecia [3]). The cases are wonderful presented, very clear, well documented and with great impact on our daily practice. It emphases the importance of a skin biopsy even when we do not think to sarcoidosis. The high incidence of ocular involvement in sarcoidosis, presented in the article, oblige us to take into considerration the routine ophtalmologic examination in all cases of sarcoidosis. Biologic therapies, such as Infliximab, have been recently accepted as another treatment option for cutaneous sarcoidosis, especially in non-response to topical or/and systemic corticosteroids. On the other hand a case of paradoxical cutaneous sarcoidosis was described as a side effect during anti-TNF-α agents (Etanercept) [1]. We agree with the corticosteroids treatment in cutaneous sarcoidosis, but we have in mind an agressive systemic therapy in case of pulmonary sarcoidosis. We congratulate the authors for their outstanding case reports that are of great scientific and didactical values for us.

REFERENCES:
1. Lamrock E, Brown P: Development of cutaneous sarcoidosis during treatment with tumour necrosis alpha factor antagonists. Australas J Dermatol. 2012;53:e87-90.
2. Henrichs MP, Streitbürger A, Gosheger G, Surke C, Dierkes C, Hardes J: Scar sarcoidosis on a finger mimicking a rapidly growing soft tissue tumour: a case report. BMC Res Notes. 2012;5:545.
3. House NS, Welsh JP, English JC: 3rd Sarcoidosis-induced alopecia Dermatol Online J. 2012;18:4.


LICHEN PLANUS PIGMENTOSUS: TWO ATYPICAL PRESENTATION
 
Prof. Huiting Dong (China)
It's interesting to see a lichen planus pigmentosus with band like lesions. This pattern is unique and has never been reported, to the best of my knowledge.


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