since 03.October 2014

 

C O N T E N T S   4.2014

 

 

 

 


ORIGINAL ARTICLES


Khalifa E. Sharquie, Adil A. Noaimi, Entesar A. Al-Janabi
Treatment of Active Acne Vulgaris by Chemical Peeling Using 88% Lactic Acid

      Our Dermatol Online 2014; 5(4): 337-342          DOI: 10.7241/ourd.20144.85

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I am persuaded that strong and drastic therapies to eradicate some dermal-cosmetical diseases are always better than light and expensive treatments byuseless cosmetic items, like gentle scrubs containing alpha, betha or gamma-hydroxyacids or certain miscellaneous of bio-extracts of exotic fruits or herbs, and/or revolting and redundant antioxidant agnets,  or moreover  creams or lotions containing  extremely poor dosages of benzoyl peroxide generally  suggested for the  administration  to the younger  for very long time in order only  to let the producer of cosmetics grow rich and notorious. When acne vulgaris (or ribelle) is not a mere aesthetic disturb, but enbodies  a real malady connected with severe psychological malaise, the usage of strong remedies, included antibiotics and escariotic agents, is welcome, even because it is conceivable that the syndrome will not appear again after this sort of dramatic treatment. It is undeniable, besides,  that Zinc….if combined with antibiotics will reduce antibiotic resistance and does increase antibiotic absortion into the skin, and I can assert it, by direct experience made in corpore vili.Many congratulations for the courage and determination dermatological surgeons in Iraq have demonstrated to combat Acne vulgaris.  Lorenzo Martini, M.Sc.  (Italy) 

The authors deserve appreciation for there deep insight in using this modality in the treatment of acne and acne scarring for showing efficacy and safety of 88% in lactic acid as a chemical peel.Their post operative instructions for use of potassium permanganate solution / acetic acid needs more elaboration.This treatment must be offered to the patients who don’t like the use of oral or topical treatment in long term regimens.A longer follow up of  at least six month would have given better insight about the relapse rates. In our country, pure lactic acid full strength (92%) pH 3.5 is being used with similar efficacy and safety.   Dr Rakesh Tilak Raj (India) 

The excellent results of peelings in many skin conditions is well known. In the case of acne, however, it is important to emphasize that this condition is caused by a confluence of elements that intervene to produce follicular plugging, inflammation and many times scarring. The course of acne is chronic and not just limited to certain period of time [1], therefore dermatologists should be cautious in counseling patients about the physiopathology of acne, how it behaves in time, as well as what are the evidence based, most effective resources available to treat it. More evidence is needed to assess the persistence of the reduction of the inflammatory and non-inflammatory lesions in time with 88% lactic acid peel. While 88% lactic acid peel might be safe in the treatment of acne it should not be recommended as a first line of treatment and a proper counseling and patient selection should be done.   Reference:  Thiboutot D, Gollnick H, Bettoli V, Dréno B, Kang S, Leyden JJ, et al. New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group. J Am Acad Dermatol. 2009;60:S1-50.   Dr Manuel Valdebran (República Dominicana) 

 
Neerja Puri, Ashutosh Talwar, MRS Monika
A study on the profile and sexual behaviour of patients in an ICTC Centre in a District Hospital in North India
      Our Dermatol Online 2014; 5(4): 343-346          DOI: 10.7241/ourd.20144.86
 

[abstract-English] , [article in English],    [PDF], [HTML]

Hayder R. Al-Hamamy, Khalifa E. Sharquie, Adil A. Noaimi, Wajeeh N. Hussein
Topical erythromycin-zinc acetate complex lotion versus topical erythromycin gel in treatment of mild to moderate acne vulgaris

      Our Dermatol Online 2014; 5(4): 347-351          DOI: 10.7241/ourd.20144.87

[abstract-English] , [article in English],   [PDF][HTML]

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I am persuaded that strong and drastic therapies to eradicate some dermal-cosmetical diseases are always better than light and expensive treatments byuseless cosmetic items, like gentle scrubs containing alpha, betha or gamma-hydroxyacids or certain miscellaneous of bio-extracts of exotic fruits or herbs, and/or revolting and redundant antioxidant agnets, or moreover creams or lotions containing  extremely poor dosages of benzoyl peroxide generally suggested for the administration to the younger for very long time in order only to let the producer of cosmetics grow rich and notorious. When acne vulgaris (or ribelle) is not a mere aesthetic disturb, but enbodies a real malady connected with severe psychological malaise, the usage of strong remedies, included antibiotics and escariotic agents, is welcome, even because it is conceivable that the syndrome will not appear again after this sort of dramatic treatment. It is undeniable, besides, that Zinc….if combined with antibiotics will reduce antibiotic resistance and does increase antibiotic absortion into the skin, and I can assert it, by direct experience made in corpore vili.Many congratulations for the courage and determination dermatological surgeons in Iraq have demonstrated to combat Acne vulgaris.  Lorenzo Martini, M.Sc.  (Italy) 

More information have been given regarding the role of bacteria, in the pathogenesis of acne. Other pathogenic factors such as inflammation pathways have been more clearly understood, giving us a perspective of acne as a more inflammatory process rather than an infectious process [1]. It is very important to coordinate an appropriate therapeutical approach to patients with acne, when using antibiotics clinicians should remember not to use them as a monotherapy but in combination with topical retinoids and in conjunction with benzoyl peroxide [2]. Recent studies have suggested superior efficacy of benzoyl peroxide and clindamycin combination over erythromycin and zinc; data from Langer and coworkers suggests that benzoyl peroxide inhibits the rise in resistant bacteria that can occur with topical antibacterial treatment unlike with the zinc combination. Antibiotics are not the mainstay treatment in acne and they should not be use as a monotherapy. Concerning issues have arisen select resistance in coagulase-negative staphylococci after 12 weeks of treatment with topical erythromycin [3].   References:   1. Dreno B, Thiboutot D, Gollnick H, Bettoli V, Kang S, Leyden JJ, et al. Global Alliance to Improve Outcomes in Acne. Antibiotic stewardship in dermatology: limiting antibiotic use in acne. Eur J Dermatol. 2014;24:330-4.   2. Thiboutot D, Gollnick H, Bettoli V, Dréno B, Kang S, Leyden JJ, et al. New insights into the management of acne: an update from the Global Alliance to Improve Outcomes in Acne group. J Am Acad Dermatol. 2009;60:S1-50.   3. Langner A, Sheehan-Dare R, Layton A. A randomized, single-blind comparison of topical clindamycin + benzoyl peroxide (Duac) and erythromycin + zinc acetate (Zineryt) in the treatment of mild to moderate facial acne vulgaris. J Eur Acad Dermatol Venereol. 2007;21:311-9.   Dr Manuel Valdebran (República Dominicana) 

 

Comment by: Ass. Prof. Antonio Chuh and Prof. Vijay Zawar 
      Our Dermatol Online 2014; 5(4): 352
 
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Zoya Hossenbaccus, Rajesh Jeewon
Skin infections among infants and parental awareness: Is there any relationship?

      Our Dermatol Online 2014; 5(4): 251-253          DOI: 10.7241/ourd.20144.88

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The incidence of complications and treatment given could be elaborated in Immunocompromised patients.  Prof. Sunderamoorthy Srinivasan (India)  

 


BRIEF REPORTS


Amani Tresh, Omimma El Gamati, Nihal Elkattabi, Abd Alrazak Burshan
Non melanoma skin cancer trends in Tripoli /Libya

      Our Dermatol Online 2014; 5(4): 359-361          DOI: 10.7241/ourd.20144.89

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Manuel Valdebran, Martha Miniño
An epidemiological analysis of children and adolescents psoriasis in a tertiary referral dermatology institute in the Dominican Republic

      Our Dermatol Online 2014; 5(4): 362-365           DOI: 10.7241/ourd.20144.90

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 Juvenile Psoriasis is a burdensome disease in children  which affects them socially and  emotionally undermining their quality of life.The authors have done a diligent work in conducting this study and deserve kudos. However, their observation  regarding use of  anthralin in 42% of cases needs elaboration.Inclusion of family history, involvement of oral, genital and nail would have made the article more comprehensive. The error relating to the total number of children examined under the heading ( material and methods) is 76 whereas in the results the splitting shows (43+37) 80.Kindly make necessary corrections before  publication.   Dr Rakesh Tilak Raj (India)  

 

 This is an interesting study that deals with juvenile psoriasis in a tropical region and results, although very general does contribute to its frequency. If more analyses could have been undertaken to compare patterns among other countries, that would be more interesting.   Dr. Rajesh Jeewon Ph.D. (Mauritius) 

 
Lorenzo Martini
Secret and latent dangers hidden underneath the glazed cover of the modern Organic Cosmetic

      Our Dermatol Online 2014; 5(4): 366-369          DOI: 10.7241/ourd.20144.91

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 Berloque dermatitis- a type of photosensitization resulting in brown pigmentation on expose skin to sunlight after application of bergamot oil and other essential oils in perfumes and colognes and other makeups are not a common problems in skin of colour compared to white skin individual in Asian country like Sri Lanka. But “Berloque type dermatitis” after exposure to citrus fruit among the young people and school children’s are a not a uncommon problem in day to day dermatology practice.   Dr. Ajith P. Kannangara (Sri Lanka)  

 

 The author offers an excellent review of risks of natural cosmetics – those based on the use of juices from fruits and polychrome herbs. Photosensitization  risks are very well explained. In fact, tradicional cosmetics are exposing consumers to Bithionol , Halogenated salicylanilides (di-, tri-, metabromsalan and tetrachlorosalicylanilide and some others that  may also cause photo-contact sensitization , not to mention other dangerous chemicals like Chlorofluorocarbon propellants, mercury and lead salts, ChloroformMethylene Vinyl chloridechloride all of them with  animal carcinogenicity and likely hazard to human health. So, it is important to watch properly  these natural substitutes and record its adverse reactions.   Dr César Bimbi (Brasil) 

 

Anca Chiriac, Piotr Brzezinski, Liliana Foia, Anca E Chiriac, Tudor Pinteala, Caius Solovan
Unique psoriatic lesion versus multiple lesions

      Our Dermatol Online 2014; 5(4): 258-260          DOI: 10.7241/ourd.20144.92

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 Psoriasis related topics are common subject among the research community but this uncovered sub topic related to this common disease has not been addressed properly. An interesting new addition to the extensively covered topic like psoriasis.   Dr. Ajith P. Kannangara (Sri Lanka)  


CASE REPORTS


Maria Bibiana Leroux, Celina Lashak
Evolution of video capillaroscopy for 10 years in a patient with Raynaud

      Our Dermatol Online 2014; 5(4): 374-377          DOI: 10.7241/ourd.20144.93

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Sanjay N. Agrawal, Pranita P. Daware, Yogeshree R. Deshmukh, Subodhkumar Jane
Gorlin’s syndrome: Atypical case report 

      Our Dermatol Online 2014; 5(4): 378-380        DOI: 10.7241/ourd.20144.94

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Manuel Valdebran, Loryart Marte, Nery Charles-Ramirez, Antonio Giraldez, Ángel Taveras, Juan Pablo Guzman, Manuel Cochon, Fernanda Nanita-Estévez
Kikuchi – Fujimoto Disease. Case report and a brief review of the literature 

      Our Dermatol Online 2014; 5(4): 381-383          DOI: 10.7241/ourd.20144.95

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1. The author is appreciated for highlighting the importance of ultrasonography along with biopsy to bring out undetectable lymph nodes. ( intramammary).  2. This presentation gives an advice to all dermatologist to revise the diagnosis periodically if the response to the treatment is not upto the expectation.  3. In fact, Kikuchi – Fujimo disease is the rarest of the rare in dermatology.  Prof. Sunderamoorthy Srinivasan  (India) 

Congratulations to the authors. It’s an interesting report, Thank you for the review and case report presentation. Overall the presentation is informative and educating. Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disorder, characterized by regional cervical lymphadenopathy with tenderness, usually accompanied with mild fever and night sweats. Less frequent symptoms include weight loss, nausea, vomiting, sore throat. Kikuchi-Fujimoto disease is an extremely rare disease known to have a worldwide distribution with higher prevalence among Japanese and other Asiatic individuals. The role of infectious agents in the pathogenesis and evolution of Kikuchi-Fujimoto disease is a matter of debate. The onset of Kikuchi-Fujimoto disease is acute or subacute, evolving over a period of two to four weeks. Clinically, the most common presentation is unilaterally lymphadenopathy with tenderness: cervical lymph nodes are the principle site of disease in 70-90% of patients; other lymph nodes, such as the axillary and abdominal ones, may be less frequently involved. Generalized adenopathy is uncommon. KFD is generally diagnosed on the basis of an excisional biopsy of affected lymph nodes. Its recognition is crucial especially because this disease can be mistaken for systemic lupus erythematosus, malignant lymphoma or even, though rarely, for adenocarcinoma. Clinicians’ and pathologists’ awareness of this disorder may help prevent misdiagnsois and inappropriate treatment.   Dr. Yugandar Inaks (India) 

The case presented by the authors highlights the importance of including Kikuchi-Fujimoto disease as a differential diagnosis for lymphadenopathy and draw attention to clinicians that Kikuchi-Fujimoto disease can be mistaken for tuberculosis and lymphoma. Having in mind the differential diagnosis and a valuable histopathological report, unnecessary administration of certain drugs (used to treat tuberculosis) can be avoided and specific follow-up of the patient would be recommended. The article is well documented, up-to date, concise, wonderfully written and reaches the task of making us aware of this rare disease.   Prof Anca Chiriac and Prof Caius Solovan (Romania) 

 
Rakesh Tilak Raj, Baljinder Kaur, Krishan Kumar Lochan, Rakesh Kumar Bahl
Nimesulide induced Stevens Johnson syndrome (SJS); managed successfully with combined approach of steroids, intravenous immunoglobulin and placentrex gel: A case report

      Our Dermatol Online 2014; 5(4): 384-387          DOI: 10.7241/ourd.20144.96

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Vijay Zawar, Tarang Goyal, Sneha Kamra
Becker’s nevus and ipsilateral acanthosis nigricans
      Our Dermatol Online 2014; 5(4): 388-390          DOI: 10.7241/ourd.20144.97

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 We read with pleasure the article and we want to congratulate the authors for very interesting case of an unusual combination of Becker’s nevus and ipsilateral acanthosis nigricans in the same individual.   Dr. Yugandar Inaks (India) 

 
Ana Maria Abreu Velez, Vickie M. Brown, Michael S. Howard
A complex immune response in halo nevi correlates with immune reactivity on infiltrated melanocytes, adjacent hair follicles and blood vessels

      Our Dermatol Online 2014; 5(4): 391-394          DOI: 10.7241/ourd.20144.98

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Hari Kishan Kumar Yadalla, Syeda Juwariya
Xeroderma Pigmentosum: A Bane in developing country – Brief report

      Our Dermatol Online 2014; 5(4): 395-397         DOI: 10.7241/ourd.20144.99

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Swati Sharma, Raghavendra Rao
Exogenous ochronosis masquerading refractory melasma

      Our Dermatol Online 2014; 5(4): 398-400          DOI: 10.7241/ourd.20144.100

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 The article is relevant and timely. This condition described is now becoming more frequent in developing countries after the introduction of triple combination regimens in day to day practice.The dermoscopy has reduced the need for biopsy in diagnosing this condition although in refractory cases, biopsy still remains the gold standard.Since this condition is refractory to treatment in most cases the authors’ observations that the indiscriminate use of hydroquinone containing compounds without medical prescription must be restricted, is the need of the hour. This article will help the dermatologists in observing this phenomenon frequently in their patients on hydroquinone.   Dr Rakesh Tilak Raj (India)

 
Gladys Alejandra Paguaga, Orlando Rodas Pernillo, Helga María Sarti
Type D Lymphomatoid Papulosis: An uncommon Variant. A case report and review of the literature

      Our Dermatol Online 2014; 5(4): 401-407          DOI: 10.7241/ourd.20144.101

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 Authors have described a rare benign clinical entity which can be mistaken for a malignant lymphoma because of the presence of atypical lymphocytes. Awareness and clinical correlation is very importnant in arriving at a diagnosis of Lymphomatoid papulosis. Recently a Type E variant characterized by angiocentric and angiodestructive infiltrate of small-sized to medium-sized atypical lymphocytes expressing CD30 and frequently CD8 has been described by Kempf W et al (Am J Surg Pathol 2013 Jan;37(1):1-13). The detailed review of literature by the authors will be useful information for the readers.   Prof. Kanthilatha Pai (India)

 

Comment by: Ass. Prof. Małgorzata Sokołowska-Wojdyło 

      Our Dermatol Online 2014; 5(4): 408
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Mariem Mohamed, Mouna Korbi, Rim Hadhri, Hayet Akkari, Awatef Hajjaji, Monia Youssef, Montasser Amri, Hichem Belhadjali, Jameleddine Zili
A huge fibro epithelial polyp of the vulva with myxoid stroma in Tunisian nulliparous woman

      Our Dermatol Online 2014; 5(4): 409-411         DOI: 10.7241/ourd.20144.102

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Manna Valiathan, Swati Sharma, C. Balachandran
S-100 Positive Multicentric Reticulohistiocytosis – report of a rare case with brief review of literature

      Our Dermatol Online 2014; 5(4): 412-415         DOI: 10.7241/ourd.20144.103

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Kanthilatha Pai, Sathish Pai, Raghavendra Rao, Sricharit Shetty
Photodistributed Acute febrile neutrophilic dermatosis: a case report 

      Our Dermatol Online 2014; 5(4): 416-418         DOI: 10.7241/ourd.20144.104

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Ana Maria Abreu Velez, Michael S. Howard, Vickie M. Brown
Immunoreactivity to dermal vessels in a patient with pyoderma gandrenosum

      Our Dermatol Online 2014; 5(4): 419-422         DOI: 10.7241/ourd.20144.105

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César Bimbi
Sarcoidosis mimicking seborrheic dermatitis: another case of Sherlockian Dermatology

      Our Dermatol Online 2014; 5(4): 423-425         DOI: 10.7241/ourd.20144.106

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CLINICAL IMAGES


Ahu Yorulmaz, Ferda Artuz, Devrim Tuba Unal
Deep variant of Erythema Annulare Centrifugum

      Our Dermatol Online 2014; 5(4): 426-427          DOI: 10.7241/ourd.20144.107

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Jerry E. Bouquot
A Meth mouth case

      Our Dermatol Online 2014; 5(4): 428          DOI: 10.7241/ourd.20144.108

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Niloofar Mehrolhasani
Marjolin’s Ulcer

      Our Dermatol Online 2014; 5(4): 429          DOI: 10.7241/ourd.20144.109

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 Marjolin ulcer has two forms clinically. These are the ulcers, infiltrative, elevated and hardened edges; or less frequently, be exophytic or exuberant granulation tissue, as seen in this case. Most of the cases described refers to squamous cell carcinoma; although rare can also see other types of malignant transformation such as basal cell carcinoma, melanoma, adeno carcinoma and sarcomas. In ancient burns, mentioned that ultraviolet radiation could act as a trigger for neoplasia. The location in the dorsum  of the hand, as it is presented could answer this mechanism.   Dra. María Bibiana Leroux (Argentina) 

 

 Úlcera del Marjolin tiene dos formas de vista clínico. Estos son morfológicamente ulcerosa, infiltrante, con bordes elevados y endurecido; o con menos frecuencia, ser exofíticos o con tejido de granulación exuberante, como se ve en este caso.  La mayor parte de los casos descritos se refiere al carcinoma de células escamosas; aunque poco frecuentes  también se pueden ver otros tipos de transformación maligna  como el carcinoma de células basales, melanoma, adenocarcinoma y sarcomas. En quemaduras antiguas, se menciona que la radiación ultravioleta podría actuar como desencadenante de la neoplasia. La ubicación en el dorso de la mano, tal como se presenta podría responder a este mecanismo.   Dra. María Bibiana Leroux (Argentina) 


LETTERS TO THE EDITOR  –  Observations


Cesar Bimbi, Piotr Brzezinski
Laptop-induced Erythema ab Igne – a case report

      Our Dermatol Online 2014; 5(4): 430-431             DOI: 10.7241/ourd.20144.110

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 Existen escasos reportes en la literatura de Eritema ab igne inducida por lapto. Estos  dispositivos electrónicos pueden generar temperaturas   medias en el rango de 43 a 47° C, estimulo que ocasionaría la dermatosis. Si bien esta entidad es de rara presentación como señalan los autores.  En el futuro cercano,  estas laptos serán más accesibles a la población general  y por tanto es probable que estos cuadros sean mucho más frecuentes.   Dra. María Bibiana Leroux (Argentina) 

 There are few reports in the literature of lapto induced  Erythema ab igne. These electronic devices may generate temperatures in the range of 43 to 47 ° C, stimuli that cause the dermatosis.  Although the condition is rare as the authors point.  In the near future, these laptops will be more accessible to the general population and is therefore likely that these pictures are much more frequent.   Dra. María Bibiana Leroux (Argentina) 

 
Tomoko Hiraiwa, Hirotoshi Furukawa, Toshiyuki Yamamoto
Pyoderma gangrenosum triggered by surgical procedures in patients with underlying systemic diseases  

      Our Dermatol Online 2014; 5(4): 432-433             DOI: 10.7241/ourd.20144.111

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Isha Parulkar, Jason Micheals, Gladys H. Telang
Primary Cutaneous CD30 +Anaplastic Large Cell Lymphoma; Report of a single large scalp nodule 

      Our Dermatol Online 2014; 5(4): 434-436             DOI: 10.7241/ourd.20144.112

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LETTER TO THE EDITOR  –  Practical Issues


Laura Statescu, Dan Vata, Laura Gheuca Solovastru
Mycosis fungoides – case presentation

      Our Dermatol Online 2014; 5(4): 437-438             DOI: 10.7241/ourd.20144.113

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HISTORICAL ARTICLES


Ahmad Al Aboud, Nora Mohammed Al-Aboud, Hanan Barnawi, Ahlam Al Hakami
Eponyms related to genetic disorders associated with gingival enlargement; part I

      Our Dermatol Online 2014; 5(4): 439-441          DOI: 10.7241/ourd.20144.114

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Piotr Brzeziński, Anca Chiriac, Saroj K. Rath
Dermatology Eponyms – sign –Lexicon (N)

      Our Dermatol Online 2014; 5(4): 442-447          DOI: 10.7241/ourd.20144.115

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