Foot ulcer revealing recurrence of Kaposi’s sarcoma

Mohammed Chaouche, Safae Zinoune, Abdellah Dah Cherif, Younes Barbach, Sara Elloudi, Hanane Baybay, Fatima Zahra Mernissi

Department of Dermatology and Venereology, University Hospital Hassan II, Fez, Morocco

Corresponding author: Dr. Mohammed Chaouche, E-mail: medch11@hotmail.com

Submission: 16.01.2019; Acceptance: 20.04.2019

DOI:10.7241/ourd.2019e.12

Cite this article: Chaouche M, Zinoune S, Cherif AD, Barbach Y, Elloudi S, Baybay H, Mernissi FZ. Foot ulcer revealing recurrence of Kaposi's sarcoma. Our Dermatol Online. 2019;10(e):e12.1.

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Kaposi’s sarcoma (KS) is a human herpes virus-8 (HHV-8)-associated angioproliferative disorder, and its occurrence may be favored by human immunodeficiency virus (HIV) infection and iatrogenic immunosuppression [1,2].

Four primary epidemiologic subtypes are commonly described: classic, AIDS-related, African, and iatrogenic [3].

Solitary ulcer KS has rarely been reported. A case of a 65-year-old woman, followed in our department for classical Kaposi sarcoma in remission for five years after treatment with bleomycin, who had presented for a year a foot ulceration oozing (Fig. 1) and resistant to antibiotic treatment and various wound healing dressings, a biopsy a been realized returning in favor of Kaposi’s sarcoma.

Consent

The examination of the patient was conducted according to the Declaration of Helsinki principles.

REFERENCES

1. Wu XJ, Pu XM, Kang XJ, Halifu Y, An CX, Zhang DZ, et al. One hundred and five Kaposi sarcoma patients:A clinical study in Xinjiang, Northwest of China. J Eur Acad Dermatol Venereol. 2014;28:1545–52.

2. Schneider JW, Dittmer DP. Diagnosis and Treatment of Kaposi Sarcoma. Am J Clin Dermatol. 2017;18:529-39.

3. Dittmer DP, Damania B. Kaposi sarcoma-associated herpesvirus:immunobiology, oncogenesis, and therapy. J Clin Invest. 2016;126:3165–75.

Notes

Source of Support: Nil

Conflict of Interest: None declared.