Prof. Ana Maria Abreu-Velez – USA
Director reserch in Georgia Dermatopathology Associates Atlanta, GA, USA.
Georgia Dermatopathology Associates, 1534 North Decatur Rd., NE; Suite 206; Atlanta, Georgia 30307-1000, USA,
Telephone: (404) 371-0077, Toll Free: (877) 371-0027, Fax: (404) 371-1900,
Some insights: Discovered and had worked in a new variant of endemic pemphigus foliaceus. This disease exhibits autoreactivity to multiple systemic organs including the optic nerve, neural
components, the mechanoreceptors, skin and mucosae appendices, heart, kidney and blood vessels. This disease constitutes a unique model for autoimmune diseases because of its endemic focus in a restricted geographical region. I discoveved some new antigens in this disease including desmoplakins, periplakins, and envoplakin. Developed a new ELISA assay for detection of desmogleins and plakin molecules. Dr. Abreu specializes in physiology of the skin and mucosal immunopathology, immunofluorescence assays, ELISA and immunoblot assays for the diagnosis of autoimmune skin and mucous membrane diseases. Immunodermatological and mucosal autoimmunity expertise: specializes in immunologic tests, primarily, for the diagnosis of bullous, vascular, connective tissue and inherited skin diseases. Specialized in direct and indirect immunofluorescent (DIF, IIF) with multiple color an` serum studies for bullous diseases (pemphigus, pemphigoid, dermatitis herpetiformis). Collagen vascular diseases [systemic lupus erythematosus (SLE), discoid lupus (DLE), lupus erythematosus, subacute cutaneous, (SCLE), dermatomyositis, scleroderma]. Chronic ulcerative stomatitis, vasculitis, livedo vasculitis, lichen planus, differentiation of bullous pemphigoid (BP) from epidermolysis bullosa acquisita (EBA) with DIF of salt (NaCl) split biopsy. Psoriasis, vasculitis, porphirias, erythema multiformis and drug eruptions among others. Detection of autoantibodies for multiple methods. Extended experience in clinical trials at all levels. Skin and mucosae diseases included, and immunodermatology. Extended experience in basic science research including autoimmune blistering diseases. Experience mentoring pre and graduate students and residents in clinical, in basic science and in clinical trials.