<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.3 20070202//EN" "journalpublishing.dtd">
<article article-type="other" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML">
<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">OURD</journal-id>
<journal-title>Our Dermatol Online</journal-title>
<issn pub-type="epub">2081-9390</issn>
<publisher>
<publisher-name>Our Dermatology Online</publisher-name>
<publisher-loc>Poland</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">OURD-7-103</article-id>
<article-id pub-id-type="doi">10.7241/ourd.20161.27</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Clinical Image</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Plaque with pearly raised borders on the forearm</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Xue</surname>
<given-names>Ruzeng</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Valdebran</surname>
<given-names>Manuel</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Terrero</surname>
<given-names>David</given-names>
</name>
<xref ref-type="aff" rid="aff3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Yang</surname>
<given-names>Bin</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
<xref ref-type="corresp" rid="cor1"/>
</contrib>
</contrib-group>
<aff id="aff1"><label>1</label><italic>Department of Dermatology, Guangdong Provincial Dermatology Hospital, Guangzhou, China</italic></aff>
<aff id="aff2"><label>2</label><italic>Ackerman Academy of Dermatopathology, New York, NY. USA</italic></aff>
<aff id="aff3"><label>3</label><italic>Research Department of the National Evangelical University Santo Domingo, Santo Domingo, Dominican Republic</italic></aff>
<author-notes>
<corresp id="cor1">
<bold>Corresponding author:</bold> Bin Yang, M.D., E-mail: <email xlink:href="yangbin101@hotmail.com">yangbin101@hotmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<year>2016</year>
</pub-date>
<volume>7</volume>
<issue>1</issue>
<fpage>103</fpage>
<lpage>104</lpage>
<history>
<date date-type="received"><day>31</day><month>08</month><year>2015</year></date>
<date date-type="accepted"><day>18</day><month>11</month><year>2015</year></date>
</history>
<permissions>
<copyright-statement>Copyright: &#x000a9; Our Dermatol Online 1</copyright-statement>
<copyright-year>2016</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p>
</license>
</permissions>
</article-meta>
</front>
<body>
<sec id="sec1-1">
<title/>
<p>A 29-year-old male presented with an annular plaque on his arm for 7 months. Physical examination revealed 6 mm annular plaque with raised borders and a shiny stellate-purple center (<xref ref-type="fig" rid="F1">Fig. 1</xref>). Dermoscopic evaluation revealed a ring of white spiked structurless areas at the periphery; an intense structurless steel purple area was observed at the center of the lesion (<xref ref-type="fig" rid="F2">Fig. 2</xref>). Hystopathological examination showed a band-like infiltrate of lymphocytes, pigment incontinence, saw tooth rete ridges, hypergranulosis and hypekeratosis (Figs. <xref ref-type="fig" rid="F3">3</xref> and <xref ref-type="fig" rid="F4">4</xref>).</p>
<fig id="F1">
<label>Figure 1</label>
<caption>
<p>Annular plaque with raised borders and a shiny stellate-purple center.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="OURD-7-103-g001.tif"/>
</fig>
<fig id="F2">
<label>Figure 2</label>
<caption>
<p>Ring of white spiked structurless area at the periphery; with an intense structurless steel purple area at the center.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="OURD-7-103-g002.tif"/>
</fig>
<fig id="F3">
<label>Figure 3</label>
<caption>
<p>Band-like infiltrate of lymphocytes, pigment incontinence, saw tooth rete ridges hypergranulosis.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="OURD-7-103-g003.tif"/>
</fig>
<fig id="F4">
<label>Figure 4</label>
<caption>
<p>Band-like infiltrate of lymphocytes, pigment incontinence, saw tooth rete ridges hypekeratosis.</p>
</caption>
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="OURD-7-103-g004.tif"/>
</fig>
<p>Lichen planus annularis (LPA) is a rare variant of lichen planus; it might comprise less than 7&#x0025; of LP cases [<xref ref-type="bibr" rid="ref1">1</xref>,<xref ref-type="bibr" rid="ref2">2</xref>]. Most frequently described locations include the genital and intertriginous areas, however, lesions on the trunk, extremities, eyelids and neck have been reported as well [<xref ref-type="bibr" rid="ref3">3</xref>].</p>
<p>The pathogenesis of LPA has not been clearly elucidated nevertheless published data has revealed that the lichenoid tissue reaction might be triggered by a sequential activation of Langerhans cells, ultimately triggering the release of activated T cells which in turn migrate to the dermis and release several cytokines such as interleukins 1 and 2, and interferon gamma [<xref ref-type="bibr" rid="ref4">4</xref>].</p>
<p>Interesting dermoscopic findings were the spiked white structurless areas in a circular disposition corresponding to Wickham striae; histopathologically it may correlate to the overall hyperplastic epidermis. Pigmentation at the center of the lesion is better appreciated dermoscopically showing a structurless steel purple area, corresponding histopathologically to areas of pigment incontinence in the papillary and reticular dermis. The black color of melanin is perceived as steel purple due to a tyndall effect. Long wavelengths are not reflected to the open air whereas shorter wavelengths are reflected and perceived by the eye as violet or blue [<xref ref-type="bibr" rid="ref5">5</xref>].</p>
<p>In conclusion, interpretation of dermoscopic findings may help to infere histopathological changes to render an accurate diagnosis.</p>
</sec>
</body>
<back>
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<fn-group>
<fn fn-type="supported-by">
<p><bold>Source of Support:</bold> Nil,</p>
</fn>
<fn fn-type="conflict">
<p><bold>Conflict of Interest:</bold> None declared.</p>
</fn>
</fn-group>
</back>
</article>
