MyLibraryZotero17Diabaté, AlmamyNaqi, AliPittoni, JulienOur Dermatology OnlineOur Dermatology Online349-351104420192019-10-032081939010.7241/ourd.20194.7Paraneoplastic pemphigus (PNP) is a muco-cutaneous autoimmune disease associated with several types of internal malignancy. We report a case of a 57-year-old male with an atypical form of PNP associated with pulmonary adenocarcinoma. There was no involvement of the mucous membranes. Although the macroscopic and histological appearances were typical of a pemphigus, the direct immunofluorescence was positive for the IgG staining and the C3 intercellular. Circulating antibodies were detected with envoplakin, periplakin and desmoplakins 1 and 2; but the Ac anti desmoglein 1 IgG and 3 IgG, BP 180 and BP 230 and auto Ac anti-epidermis were negative. The clinical evolvement was observed with a combination of systemic corticosteroids and radiotherapy associated with Cisplatin-Alimta chemotherapy.Crossrefenhttp://www.odermatol.com/issue-in-html/2019-4-7-pemphigus/D:\OurDermatolOnline\2019\numer 2019 4\pdf\7.Atypical-DiabateA.pdf2019-10-12 11:37:45