MyLibraryZotero17González-Ruiz, LucíaFranco-Muñoz, MonserratRogel-Vence, MaríaHerrera-Montoro, VioletaOur Dermatology OnlineOur Dermatology Online187-1901022201909.04.20192081-939010.7241/ourd.20192.21Syringomas are benign adnexal tumors deriving from eccrine sweat ducts, that affect 1% of general population. They present with a female predominance and associated with Down's syndrome. Syringomas are classified into four clinical variants, the localized form is the most frequent. Clinically, the appear as multiple, small, firm, skin-colored and asymptomatic papules, usually distributed in the periorbital area. Skin biopsy show benign proliferation of multiple eccrine ducts embedded in fibrotic stroma of the upper dermis. We present a case of a 20-year-old man with Down's syndrome with multiple papules resembling eruptive syringomas. We review reported clinical and histopathological findings of eruptive syringomas and discuss differential diagnosis as well as treatment options.Zoteroeshttp://www.odermatol.com/issue-in-html/2019-2-21-dermatosis/D:\OurDermatolOnline\numer 2019 2\pdf\21.Striking-Gonzalez-RuizL.pdf