%0 Journal Article
%T Atypical paraneoplastic pemphigus associated with pulmonary adenocarcinoma
%V 10
%N 4
%P 349-351
%U http://www.odermatol.com/issue-in-html/2019-4-7-pemphigus/
%X Paraneoplastic pemphigus (PNP) is a muco-cutaneous autoimmune disease associated with several types of internal malignancy. We report a case of a 57-year-old male with an atypical form of PNP associated with pulmonary adenocarcinoma. There was no involvement of the mucous membranes. Although the macroscopic and histological appearances were typical of a pemphigus, the direct immunofluorescence was positive for the IgG staining and the C3 intercellular. Circulating antibodies were detected with envoplakin, periplakin and desmoplakins 1 and 2; but the Ac anti desmoglein 1 IgG and 3 IgG, BP 180 and BP 230 and auto Ac anti-epidermis were negative. The clinical evolvement was observed with a combination of systemic corticosteroids and radiotherapy associated with Cisplatin-Alimta chemotherapy.
%G en
%J Our Dermatology Online
%A Diabaté, Almamy
%A Naqi, Ali
%A Pittoni, Julien
%D 2019-10-03