%0 Journal Article
%T Decreased serum ferritin and vitamin D levels in patients with recurrent aphthous stomatiti
%V 10
%N 3
%P 229-233
%U http://www.odermatol.com/issue-in-html/2019-3-1-aphthous/
%X Background: Recurrent aphthous stomatitis is the most common ulcerative disease of the oral mucosa. Several predisposing factors like oral microbial flora, stress, viral infections, vitamin and mineral deficiencies have been associated with the disease. However, the etiopathogenesis of recurrent aphthous stomatitis remains unknown. Material and Methods: The study included 20 patients with recurrent aphthous stomatitis and 20 healthy individuals within the control group. Complete blood count, serum levels of ferritin, folate, vitamin B12, zinc, 25-hydroxyvitamin D, herpes simplex virus type-1 IgG and herpes simplex virus type-2 IgG were evaluated in each participant. Results: White blood cell count, platelet count, mean platelet volume, mean serum levels of hemoglobin, folate, vitamin B12 and zinc were statistically similar in patients and healthy individuals. However, the mean serum ferritin level was significantly lower in patients (26.5±25.5 ng/mL) compared to healthy individuals (42±30 ng/mL) (p=0.04). The mean serum 25-hydroxyvitamin D level was significantly lower in patients (13.6±6.5 ng/mL) compared to healthy individuals (20.9±10 ng/mL) (p=0.01). No significant difference has been observed between two groups in the frequency of positive serum herpes simplex virus type-1 IgG and herpes simplex virus type-2 IgG levels. Conclusions: No association has been observed between recurrent aphthous stomatitis and white blood cell count, mean platelet volume, serum levels of hemoglobin, folate, vitamin B12, zinc, herpes simplex virus type-1 IgG and herpes simplex virus type-2 IgG. However, decreased serum levels of ferritin and 25-hydroxyvitamin D were more prevalent in patients with recurrent aphthous stomatitis compared to healthy individuals.
%G en
%J Our Dermatology Online
%A Tamer, Funda
%A Avci, Emine
%D 2019-07-02