Blue light evoked by LED, pc screens, TV or sun rays trespassing the hole of ozone layer is fatal for skin health in Man: rhodopsins from animals or some algae represent a touchesane to exorcize this dramatic concern

© Our Dermatol Online e.2019 e28.1 How to cite this article: Brzeziński P, Martini L. Blue light evoked by LED, pc screens, TV or sun rays trespassing the hole of ozone layer is fatal for skin health in Man: rhodopsins from animals or some algae represent a touchesane to exorcize this dramatic concern. Our Dermatol Online. 2019;10(e):e28.1-e28.3. Submission: 05.07.2019; Acceptance: 12.08.2019 DOI: 10.7241/ourd. 2019e.28 Blue light evoked by LED, pc screens, TV or sun rays trespassing the hole of ozone layer is fatal for skin health in Man: rhodopsins from animals or some algae represent a touchesane to exorcize this dramatic concern


INTRODUCTION
The research on blue light isn't as advanced as the research on UV, so we don't know anywhere near as much about how exactly it causes damage to skin.
And to make it more confusing, older studies on the effects of blue and violet light aren't as valid. A lot of the time the lights used in the studies also produced UV, so it's possible that the effects they found were from the contaminating UV rays and not the visible light at alland even very small amounts of UVA1 (0.5%) can work synergistically with visible light in causing its effects.
In Caucasian individuals and albinos Blue light decelerate dramatically the cell turnover encouraging the cutaneous senescence.
In hyperpigmented people (Asians and Black skinned persons) Blue light may drive to the occurrence of malignant melanoma, to boot.
Besides all the radiations characterized by low frequence and highest wavelength (γ-rays and X-rays) are extremely rich of energy and are capable to trespass the barrier of the ozone layer and can evoke irreversible damages to all the living organisms and in Man on the skin in toto.
Blue, green and purple light (some of the visible radiations) may trespass the ozone layer and invade the circumstantial atmosphere, where we live, as the aforesaid ionizing rays.
In another future seat the AA will discuss the concern about the risk of the incidence of ionizing rays on the human metabolism and will attempt to find some peculiar natural or organic ingredients apt to protect skin from all these rays (idest micronized malakite, Copper PCA or Gold zeolite micronized).
In this paper the AA desire to propose the usage of rhodopsins extracted from animals (crabs) or algae (Clamydomomnas).
In cosmetics all the following algae are allowed to be inserted in beauty formulas for skin care for women and men: Rhodopsins are membrane receptor proteins which use a light absorbing chromophore to capture the light and as a consequence of light absorption gain enzymatic activity. Rhodopsins are found in bacteria; archaea; eukaryotes such as Peranema (a euglenoid) [1], Chlamydomonas (a green alga) [2], Allomyces (a chytrid motile fungus) [3]; and animals. The existence of similar conserved amino acids in all rhodopsins in the region surrounding the chromophore [4] indicates the likelihood of common or at least similar mechanisms of rhodopsin activation [5].
The methods of extraction are enzymatic and physical and in the plot the two kinds of substrates have been treated to yield pure rhodopsins (Table 1). Rhodopsins were exposed to green light (OE; 550 nm; 409 W/cm 2 ), to blue light (E; 403 nm; 300 W/cm 2 ), or to blue light in the presence of NH 2 OH to inhibit potential photoreversal of bleaching (F; 403 nm; 300 W/cm 2 ). Rhodopsin disappeared rapidly in green light and in blue light with NH 2 OH, conditions with minimized photoreversal of bleaching. However, in blue light without NH 2 OH, rhodopsin disappeared slowly, despite irradiation with the same photon fluxes as in the other two conditions. These rhodopsins that were not treated with NH 2 OH were transeferred in a jar and disperded in Cyclosiloxane 345 Dow Corning, in order to obtain a lotion to be spread on the skin.
The AA have studied deeply the concern about the capacity of rhodopsins both from Cancer pagarus and Clamydomonas reinhardtii to absorb blue light, but we must keep on account that blue light may come from every technological apparatus (computer screen, tv and the minimal quote of rays that trespass the ozone layer together with the ionizing radiations during all the hour of whichever day, in winter or summer and when it rains or it is cloudy).

MATERIALS AND METHODS
The AA have ideated the following sort of oleolite made of silicones and rhodopsins extract in n-propanolol. 0.8% of rhodopsines (the ones from the crab treated enzymatically and physically and the ones treated chemically in acidic milieu in order to obtain a protein and polysaccharide degradation) is disperded in Cyclosiloxane 345 Dow Corning Chemical and spread on the faces and necks of 5 volunteers: 3 albinos: (we must remark that albinos are requested to walk on a city park all the day long, exposing themselves to sun rays): a) 21 y. old; b) 43 y. old; c) 58 y. old; d) a pale young mannequin (22 y. old) who had to walk on catwalk during fashion défilés under strong LED lights and who showed every evening a reddish and blistered skin especially on cheekbones 8after 7-8-9 hours of work); e) an employee of IRS (37 y. old) who uses to stay 8-9 hours in front of his pc cause of his job.

RESULTS
All volunteers had prior answered to a questionnaire (University of Rochester Medical Center) about the degree of inflammation due to aggression by sun rays during all the hours of daylight. In Table 2 it is possible to observe the different scores recorded in the 5 volunteers after 9 hour of exposure to blue light for one entire day of work or rest without the usage of the oleolite containing rhodopsis and in Table 3 it is possible to behold the scores recorded in the same 5 volunteers after 9 hours of exposure to blue light after having applied the oleolite.

DISCUSSIONS
It is quite amazing to notice that Case e does not burn easily standing in front of his pc without spreading the oleolite (score 17) but one can observe that applying the lotion, the score disminishes drastically [6] and this means that pc screen releases blue light less than other sources as sun or LED [6][7][8][9][10].

AKNOWLEDGEMENTS
All these experiments have been possible to be done owing to the chance to use the laboratories and the machines of the Department of Excellence of Pharmaceutical Biotechnologies of the University of Siena.