%0 Journal Article
%T Lichen planus pigmentosus and association with autoimmune diseases: A case–control study
%V 10
%N 2
%P 125-130
%U http://www.odermatol.com/issue-in-html/2019-2-4-lichen/
%X Background: Studies on the co morbidities seen with lichen Planus Pigmentosus (LPP) are limited. Aims: We sought to determine the prevalence of auto immune diseases (AD) associated with LPP. Methods: A total of 30 patients with LPP and 30 age and sex matched controls were examined. Both groups were evaluated for the presence of AD using physical examination and immunological tests. Results: We collected 30 LPP patients. There were 9 men and 21 women. Prevalence of AD was higher in LPP patients (40.0%) than in the control group (3.3%). LPP was significantly associated with AD, the age and gender adjusted OR was 22.9; P: 0.005. Twelve patients had an associated AD. There was no statistically significant difference between the group with ADs and without ADs concerning the sex, the age of onset of the disease, the extent of the lesions and the evolution. The immunological tests were positive in only one patient. Limitations: This study was performed in a little sample with a geographically restricted population. Conclusion: We found a frequent association of LPP with ADs. We suggest that autoimmunity might be a pathogenic factor of LPP.
%G en
%J Our Dermatology Online
%A Youssef, Monia
%A Lahouel, Ines
%A Korbi, Mouna
%A Soua, Yosra
%A Marmouch, Hela
%A Akkari, Hayet
%A Mohamed, Meriem
%A Belhajali, Hichem
%A Belghith, Asma
%A Zili, Jameleddine
%D 09.03.2019