Dermatology Eponyms – sign – Lexicon (U)

Piotr Brzezinski1,2, Lorenzo Martini2

1Institute of Biology and Environmental Protection, Pomeranian Academy, Slupsk, Poland; 2University of Siena, Department of Pharmaceutical Biotechnologies, Via A. Moro 2, 53100 Siena, Italy

Corresponding author: Piotr Brzezinski, MD PhD, E-mail: brzezoo77@yahoo.com

Submission: 13.01.2019; Acceptance: 10.03.2019

DOI: 10.7241/ourd.20193.34

Cite this article: Brzezinski P, Martini L. Dermatology Eponyms – sign – Lexicon (U). Our Dermatol Online. 2019;10(3):323-324.

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© Our Dermatology Online 2019. No commercial re-use. See rights and permissions. Published by Our Dermatology Online.


Eponyms are used almost daily in the clinical practice of dermatology. And yet, information about the person behind the eponyms is difficult to find. Indeed, who is? What is this person’s nationality? Is this person alive or dead? How can one find the paper in which this person first described the disease? Eponyms are used to describe not only disease, but also clinical signs, surgical procedures, staining techniques, pharmacological formulations, and even pieces of equipment. In this article we present the symptoms starting with (U) and other. The symptoms and their synonyms, and those who have described this symptom or phenomenon.

Key words:Eponyms, Skin diseases, Sign, Phenomenon


In 1998, Grob and Bonerandi introduced the “ugly duckling” concept to demonstrate that nevi in the same individual tend to resemble one another and that atypical mole often deviates from the individual’s nevus pattern. In other words, nevus that does not resemble other nevi is more likely to be suspicious of melanoma [1,2].


Bubonic plague. Black tongue in Bubonic plague. A similar sign – Antichrist sign, where black lips are a classic indication of an infection with Yersinia pestis [35].


Thickening of the ulnar nerve at the elbow [6,7]. A sign of tuberculoid leprosy. Also known as Elbow sign.


Umbilical sign is seen in Marfan syndrome. It is the unusual ability to touch the umbilicus with the right hand, crossing the back, and approaching from the left side, indicating increased length of upper extremity [8].


The tongue is dry in cases of uremia [9].


The presence in the urine of malarial patients of minute black granules of blood pigment [10].


1. Scope A, Dusza SW, Halpern AC, Rabinovitz H, Braun RP, Zalaudek I, The “ugly duckling” sign: Agreement between observersArch Dermatol 2008; 144: 58-64.

2. Gaudy-Marqueste C, Wazaefi Y, Bruneu Y, Triller R, Thomas L, Pellacani G, Ugly Duckling sign as a major factor of efficiency in melanoma detectionJAMA Dermatol 2017; 153: 279-84.

3. Brzeziński P, Wollina U, Espinoza-Benavides L, Chang P, Mohamed M, Geller SA, Dermatology Eponyms –sign –Lexicon (S). Part IIOur Dermatol Online 2018; 9: 470-7.

4. Brzeziński P, Sinjab AT, Campbell CM, Kentorp N, Sand C, Karwan K, Dermatology Eponyms –phenomen/sign –Lexicon (supplement)Our Dermatol Online 2012; 3: 147-55.

5. Brzeziński P, Pessoa L, Galvão V, Barja Lopez JM, Adaskevich UP, Niamba PA, Dermatology Eponyms –Sign –Lexicon –(H)Our Dermatol. Online 2013; 4: 130-43.

6. Bachaspatimayum R, Hafi B, A case of HIV, leprosy co-infection –presenting as immune reconstitution inflammatory syndromeOur Dermatol Online 2018; 9: 272-4.

7. Puri N, Kaur M, A retrospective study of profile of leprosy patients in a District Hospital in North IndiaOur Dermatol Online 2015; 6: 16-8.

8. Brzezinski P, Bourée P, Chiriac A, Bouquot JE, Schepis C, Hofer T, Chatproedprai S, Mizutani H, Dermatology Eponyms –Sign –Lexicon –(M)Our Dermatol Online 2014; 5: 312-26.

9. Mortensen H, [Oral changes in uremia]Tandlaegebladet 1971; 75: 461-70.

10. Pradhan N, Hazra RK, Can a non-invasive urine-based test become the next-generation diagnostic tool for malaria?Infez Med 2018; 26: 199-203.


Source of Support: Nil

Conflict of Interest: None declared.

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