2014.1-3b.Comment

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Our Dermatol Online 2014; 5(1): 18
Date of submission:  26.12.2014 / acceptance: 06.01.2014
Conflicts of interest: None
 
PSORIASIS UNCOVERED – COMORBID CONDITIONS WITH SPECIAL REFERENCE TO METABOLIC SYNDROME
by

Belliappa Pemmanda Raju, Umashankar Nagaraju

COMMENT:

Dr. Manuel Valdebran

Instituto Dermatológico y Cirugía de Piel “Dr. Huberto Bogaert Díaz”,
C/Federico Velásquez, esq. Albert Thomas, Santo Domingo, República Dominicana
E-mail: investigacion@valdebran.com 

 
The association of psoriasis with cardiovascular disease, in particular, has been subject of research for many years, however, inconclusive results were always obtained as cardiovascular disease risk factors could act as confounders. Recently the topic have caught more attention as better designed studies have been performed thus confirming its association. Among these studies, it is very interesting to cite the meta-analysis performed by Miller et al [1] where they revised 75 relevant articles including more than 500,000 cases and found that psoriasis was associated with cardiovascular disease, ischemic heart disease, peripheral vascular disease, atherosclerosis, diabetes, hypertension, dyslipidemia, obesity by body mass index and by abdominal fat and metabolic syndrome but not associated with cerebrovascular disease and cardiovascular mortality. It is important to note that these associations were stronger in hospital based studies whereas population based studies did not show significant associations with the exception of dyslipidemia. The present article which shows the results of a hospital based study shows results similar of what has been published in the international literature. It is very important to have regional statistical data and I personally hope that this study may become a reference for larger hospital and population based studies in India. It is important to call attention to dermatologists and medical practitioners in general about the association of psoriasis and cardiovascular disease, and metabolic syndrome. I agree with the authors with the fact that we should get a more detailed and systematic evaluation of psoriatic patients addressing possible risk factors for metabolic syndrome and cardiovascular disease.
 
REFERENCE
1. Boneberger S, Rupec RA, Ruzicka T. Complementary therapy for atopic dermatitis and other allergen skin diseases: facts and controversies. Clin Dermatol. 2010;28:57-61.


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