2013.1-29.Canada

Hunter syndrome [7]

Hunter syndrome, also known as mucopolysaccharidosis (MPS) II, is one of at least 10 defined mucopolysaccharidoses. It is named after, Charles A. Hunter (1873-1955), a Scottish-Canadian physician.

Dr. Charles Hunter, in Manitoba, Canada, first described Hunter syndrome in 1917 when he documented short stature, unusual facial features, hepatomegaly, deafness, heart disease, and nodular skin lesions in two brothers. Cutaneous features of this syndrome are firm, hypopigmented to skin-colored papules and nodules generally found on the back, particularly near the scapulae, as well as on the chest, neck, arms, or thighs. These occur generally before 10 years of age in both the mild and severe forms of Hunter syndrome.

Masson’s neuronevus and

Masson’s pseudoangiosarcoma

[8]

Masson’s neuronevus was used to refer to the neurotized nevus. Masson’s

pseudoangiosarcoma or the Masson lesion are the other names for intravascular papillary endothelial hyperplasia.

These were named after Claude L. Pierre Masson (1880-1959), (Fig. 4), French-born Canadian pathologist.

He was the chair of anatomic pathology at the hospital and medical school at Strasbourg, France. In 1927, while he was 46 years old, Masson resigned his position at Strasbourg and accepted the position of chief of anatomic pathology at the University of Montreal Medical School. Pierre Masson died at the age of 79 years. He is buried, as he wished, at the cemetery of Notre-Dame-des-Neiges, atop Mont Royal, where today one has a grand view of the University of Montreal.

Osler’s nodes

and Osler-Weber-Rendu syndrome [9]

Osler’s nodes are painful, red, raised lesions found on the hands and feet. They are associated with a number of conditions, including infective endocarditis.

Osler-Weber-Rendu syndrome or Osler-Weber-Rendu disease are another names for Hereditary hemorrhagic telangiectasia which is a familial syndrome characterized by multiple telangiectasia of the skin, and of the oral, nasal and gastrointestinal mucous membranes.

The above conditions and some other medical conditions are named after Sir William Osler.

Osler was a Canadian physician, (1849-1919), (Fig. 5) a native of Canada who at the age of 35 came to USA for 21 years and then moved to the England for the final 14 years.

Frederick Parkes Weber (1863-1962) was English physician. Henri Jules Louis Marie Rendu (1844-1902) was a French physician.

Senear-Usher syndrome [10]

This is eponym for what is also known as pemphigus erythematodes. It is named after the American dermatologist, Frances Eugene Senear (1889–1958) and the Canadian dermatologist, Barney David Usher (1899–1978). Usher, (Fig. 6), is the first Canadian dermatologist to have his name eponymically attached to a disease. He was born and received his early medical education in Montreal and his MD from McGill University in 1922. In 1926, in collaboration with Senear, Usher published the classic report on pemphigus erythematodes.