Neerja Puri, Asha Puri
COMMENT:
Cheng-Che E. Lan, MD, PhD
How to cite an article: Lan CC-E. Comment: A comparative study on 100% tca versus 88% phenol for the treatment of vitiligo. Our Dermatol Online 2012; 3(3): 187.
The study performed by Puri and Puri appearing in this issue suggested that TCA and phenol, the two medium depth chemical peeling agents, may be used to induce repigmentation of stable vitiligo lesions. Although different modalities have been introduced for vitiligo treatment, surgical intervention is still considered as an important treatment option for stable vitiligo lesions that do not respond to conventional therapies. Different surgical techniques, some requiring cellular cultures, have been established for treating stable vitiligo. More recently, dermabrasion has also been suggested to be an alternative intervention, especially if followed by phototherapy [1]. While it is of academic importance to clarify if the mechanisms involved in repigmentation differ between these different surgical approaches, it is perhaps even more crucial to identify “stable” vitiligo lesions that will most likely respond to surgical interventions.
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