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DERMATOLOGY EPONYMS – PHENOMEN / SIGN – DICTIONARY (A) – CONTINUED

Brzeziński Piotr1, Wass John2, White Katherine2, Daboul Mohamed Wael3, Arlt Wiebke4, van den Hombergh Peter5, Parker Sareeta6, Khamesipour Ali7

16th Military Support Unit, Ustka, Poland, brzezoo@wp.pl
2Addison’s Disease Self-Help Group, Guildford, UK. kgwhite@addisons.org.uk
3Laboratory Medicine Specialist, Damascus, Syrian Arab Republic. idaboul@scs-net.org
4Clinical and Experimental Medicine University, of Birmingham, UK w.arlt@bham.ac.uk
5Chairman Dutch Society of Tropical Medicine and Int. Health Kolhornseweg, Hilversum, Holand p.hombergh@chello.nl
6Department of Dermatology, Emory University, Atlanta, USA. srsingh@emory.edu
7Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran khamesipour_ali@yahoo.com
How to cite an article: Brzeziński P, Wass J, White K, Daboul MW, Arlt W, van den Hombergh P, Parker S, Khamesipour A. Dermatology eponyms – phenomen / sign – Dictionary (A) – continued. Our Dermatol Online 2011; 2(1): 27-34.


 
ACETANILIDE SIGN
Blueness of face and lips with faintness, a sign of poisoning with acetanilide
 
ACID BURNS SIGN
Burning in the mouth and throat with vomit containing white lum
ps of mucosus and altered black or brown blood. Possible staining of lips, skin or clothing from the acid. A sign of poisoning with a strong mineral acid
 
ACNE CORNEE SIGN
= synonim: contagious follicular keratosis, ichtiosis sebacea cornea (H. Leloir, E. Vidal, E. Wilson). The whole body becomes covered with small spinelike growths of a dirty yellow color. The spines are very hard and, when cut off and placed in a container, rattle like scraps of metal. Leloir and Vidal shorten the name to acne cornee. Wilson speaks of it as ichthyosis sebacea cornea.
 
Figure 1. Acne cornee sign
 
HENRI CAMILLE CHRYSOSTÔME LELOIR
French dermatologist (1855-1896). Studied at Lille and Paris, obtaining his doctorate in 1881. In 1882 he became Chef de clinique at the Hôpital St.-Louis, in 1885 was appointed professor.
 
Figure 2. Henri Leloir
 
JEAN BAPTISTE EMILE VIDAL
(18 June 1825 – 16 June 1893) French dermatologist who was a native of Paris. He studied medicine in Tours and Paris, becoming médecin des hôpitaux in 1862. For much of his career he was associated with the Hôpital Saint- Louis (1867-90) in Paris. In 1883 he became a member of the Académie de Médecine. He is remembered for his investigations of lupus and skin lichenification. His name is associated with: pityriasis circinata et marginata of Vidal – a localized variant of pityriasis rosea and Vidal’s disease, synonymous lichen simplex chronicus. He distinguished himself in his successful struggle to separate the contagious patients in the hospitals.
 
 
Figure 3. Jean Vidal
 
WILSON WILLIAM JAMES ERASMUS
Brutish dermatologist and anatomist (1809-1884). Was born in London, Bartholomew’s Hospital in London. We owe to Wilson in great measure the habit of the daily bath.Died at Westgate-on-Sea in 1884.
 
 
Figure 4. Erasmus Wilson
 
ADDISON’S SIGN
Characterized by bronze-like pigmentations of the skin.
 
ADDISON’S ORAL SIGN
Hyperpigmentation of the buccal mucosa due to lack of adrenal cortical control over the pituitary secretion of melanocyte stimulating hormone. 
 
ADDISON’S PALM SIGN
Characteristic pigmentation in the creases of the hand.
 
Figure 5. Addison disease
 
Figure 6. Addison’s palm sign
 
THOMAS ADDISON
English physician (1795-1860). Was the first to describe a disease of the endocrine glands and the type of anemia now known as Addison’s disease. Thomas Addison was born in April 1793 at Long Benton near Newcastle-upon- Tyne. Thomas studied medicine at the University of Edinburgh and took his doctorate in medicine in 1815. In 1829, in collaboration with John Morgan, he published the first work on toxicology in English.
 
Figure 7. Thomas Addison
 
ALCOHOLISM BURN SIGN
the characteristic burn from a cigarette occurring between the fingers after the person has fallen into a deep alcoholic sleep.
 
ALIBERT’S SIGN = synonym mucosis fungoides
 
Figure 8. Mucosis fungoides (Alibert’s sign)
 
JEAN LOUIS MARC ALIBERT
French dermatologist (1768-1837). In 1798, while still a student Alibert was co-founder of the Société médicale d’émulation de Paris of which he was a secretary for many years.His doctoral thesis of 1799, Dissertation sur les fièvres pernicieuses, ou ataxiques intermittentes, was such a success that it subsequently appeared in five improved and enlarged editions (1801, 1804, 1809, 1820) and in 1808 was translated into English by Charles Caldwell in Philadelphia. Alibert did his work on diseases of the skin at time when Willan’s system was still unknown in France. Contrary to Robert Willan, whose system was based on pathological anatomy, Alibert preferred to divide by appearance. He attempted to introduce Jussieu’s classification in the classification of diseases. He divides them into families, genera, and species, and introduced a large number of new designations. He originated several terms, like the term asbestos rash. Alibert also contributed significantly to the spreading of vaccination against smallpox.
 
Figure 9. Jean Alibert
 
ALLIGATOR SIGN
Martin described a remarkable variety of ichthyosis in which the skin was covered with strong hairs like the bristles of a boar. When numerous and thick the scales sometimes assumed a greenish-black hue. An example of this condition was the individual who exhibited under the name of the „alligator-boy.” The skin affected in this case resembled in color and consistency that of a young alligator. Also called Martin’s sign (Martin and Taylor).
 
Figure 10. Alligator sign
 
AMPICILLIN MONO RASH SIGN
The appearance of an irritating rash of macular and popular form seen in sensivity to ampicillin, often indicates the patient has infectious mononucleosis, because the rash appears more frequently in patients with infectious mononucleosis that been treated with ampicillin.
 
ANDERS’S SIGN
=synonim adiposis tuberosa simplex (Small sensitive or painful masses of fat that occur on the abdomen or the extremities.)
 
JAMES MESCHTER ANDERS
American physicaian (1854-1936). The third President of the American Society of Tropical Medicine. He was born at Fairview Village, Pennsylvania, on July 22, 1854. He received his MD degree from the University of Pennsylvania in 1877, where he later also received his PhD degree. In 1900 Anders was elected Chair of the Medical Section of the American Medical Association, and in 1908 was the President of the Inte rnational Congress on Tuberculosis. He died on August 29, 1936, at the age of 82.
 
Figure 11. James Anders
 
ANILINE SIGN
Blueness of face lips with drowsiness. A aniline oil poisoning.
 
ANNAM SIGN
=synonym: oriental boil, cutaneous leishmaniasis, Delhi boil, old world leishmaniasis, oriental sore, tropical sore, oriental boil, Bagdad boil, Delhi sore, Bombay boil, deli fever, Biskra button, furunculus Orientalis, Jericho boil, Tashkent ulcer, herpes du nil, die Orientbeule, die Aleppobeule, orientbyld, pendsjabzweer, lupus endemicus, leishmaniasis furunculosa, Bombaybuil, Bassorabuil, Cochinzweer, Bagdadbuil, Asjbadkazweer, leishmaniasis tropica, Aleppobuil, bouton du Nil, φ?μα της Ανατολ?ς, fuma tis anatolis, (Saunders 1945, E.J. Marzinowsky and Bogbow 1904).
 
Figure 12. Cutaneous leishmaniasis (L.major)
Figure 13. Cutaneous leishmaniasis (L.major)
Figure 14. Cutaneous leishmaniasis (histology)
 
ANTRHAX SIGN
A circumscribed boil with relatively little pain and an absence of pus. A sign of cutanesus anthrax.
 

 

Figure 15. Antrhax signs
Figure 16. Antrhax signs
Figure 17. Antrhax signs
 
ARGYRIA SIGN
A blue deposit of silver in the skin, caused by exposure to silver dusts or salts. Often appears as a gray blue haze in the white of the eye. Also known as SILVER EYE SIGN
 
ARMADILLO SIGN
Paternal hereditary ichtyosis, morbid development of the papillae and thickening of the epidermic lamellae. Also called Pettigrew’s sign (Pattigrew 1832 i Ascanius). Pettigrew mentions a man with warty elongations encasing his whole body. At the parts where friction occurred the points of the elongations were worn off. This man was called „the biped armadillo.” The females had normal skins. All the members of the well-known family of Lambert had the body covered with spines.
 
ARSENIC SIGN
A classic sign of chronic arsenical poisoning in which the palms and the soles of the feet have a leathery texture. Also known as LEATHERY PALM SIGN.
 
Figure 18. Arsenic sign
Figure 19. Arsenic sign
 
ARUM MACULATUM SIGN
Purging, cold clammy skin, with swelling of the tongue. Indicates poisoning from arum maculatum. Also known as CUCKOO PINT SIGN.
 
Figure 20. Arum maculatum
 
ASSAM’S SIGN
Chloasma. Macula Gravidarum; Macula Uterina; Macula Hepatica. During pregnancy the skin can become bronze with black spots like a leopard (ASSAM 1884 and KAPOSI).
 
Figure 21.Chloasma
 
MORITZ KAPOSI
(born 23 October 1837 in Kaposvár, Hungary – 6 March 1902 in Vienna, Austria) was an important Hungarian dermatologist, discoverer of the skin tumor that received his name (Kaposi’s sarcoma). Born to a Jewish family, originally his surname was Kohn, but with his conversion to the Fig. 22 Moritz Kaposi Catholic faith he changed it to Kaposi. In 1855 Kaposi began to study medicine at the University of Vienna and attained a doctorate in 1859. In his dissertation, titled Dermatologie und Syphilis (1866) he made an important contribution to the field. Kaposi was appointed as professor at the University of Vienna in 1875, and in 1881 he became member of the board of the Vienna General Hospital and director of its clinic of skin diseases. He was authored the book Lehrbuch der Hautkrankheiten (Textbook of Skin Diseases) in 1878. Kaposi’s main work, however, was Pathologie und Therapie der Hautkrankheiten in Vorlesungen für praktische Ärzte und Studierende (Pathology and Therapy of the Skin Diseases in Lectures for Practical Physicians and Students), published in 1880, which became one of the most significant books in the history of dermatology. He is credited with the description of xeroderma . pigmentosum („Ueber Xeroderma . pigmentosum. . Medizinische . Jahrbücher, Wien, 1882: 619-633”). In all, he published over 150 books and papers.
 
Figure 22. Moritz Kaposi
 
ACKNOWLEDGEMENT:
Figure 18,19 Dr. D. N. Guha Mazumder Director DNGM Research Foundation and Prof. & Head, Dept. of Medicine & Gastroenterology, (Retd.), Institute of Post Graduate Medical Education & Research (IPGME&R), Kolkata. Address : Kolkata -700 053, India. E-Mail : guhamazumder@yahoo.com
Figure 10 Dr. Vinzenz Oji Department of Dermatology, University of Münster, Münster, Germany and Interdisciplinary Center of Clinical Research, University of Münster, Münster, Germany, E-Mail : ojiv@uni-muenster.de
 
REFERENCES
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