2010.2-5.Clear cell

                                                                                                                            article in PDF  
N Dermatol Online. 2010; 1(2): 29-30
Conflicts of interest: None
 
 

 

CASE REPORT OF CLEAR CELL ACANTHOMA

CLEAR CELL ACANTHOMA – OPIS PRZYPADKU

Piotr Brzezinski1

16th Military Support Unit, Ustka, Poland

Corresponding author: Dr. Piotr Brzezinski     e-mail:brzezoo77@yahoo.com


 
Clear cell acanthoma (CCA) is characterized by pink-brown nodules and usually occurs on the legs of elderly people. CCA was first described by Degos as a benign tumor of epidermal origin. Clear cell acanthoma are also known as Degos acanthoma, tumor Degos or acanthome à cellules claires. Some authors have also suggested that it is a localized form of inflammatory psoriasiform dermatoses. The diagnosis is rarely made before skin biopsy. When examined under the microscope, clear cell acanthoma show a characteristic accumulation of clear glycogencontaining cells in the epidermis. The common dermatoscopic feature of all these articles is the presence of pinpoint-like/dotted vessels, which are described as having a homogenous/bunch-like, reticular, pearl lessions. So far, only a few cases presented the dermoscopy analysis of ACC. A 45 year-old woman presented with a 4-year history of a lesion on the posterior aspect of his leg (fig. 1). Dermatological examination revealed a red-brown, vascularized lession and central squaming with a diameter of 1,5 x 2 cm. Dermatoscopy disclosed multiple dotted vessels arranged partly in a linear and partly in a reticular appearance (fig. 2). Characteristics include of CCA: asymptomatic course, slow growth, single, pinkbrown nodules or small plaques often located in the lower extremities of elderly patients and the dermoscopy image. Characteristic features of CCA also occurred in the analyzed patient.Irritated seborrheic keratose, basalcell carcinoma, Bowen's disease, squamous-cell carcinoma, keratoacanthoma and amelanotic melanoma or nodular melanoma should be considered in the differential diagnosis of CCA.
 
Figure 1. Nodule on the leg
Figure 2. Clear cell acanthoma in dermoscopy


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